Sökning: "peroxynitrite"

Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet peroxynitrite.

1. 1. Redox Reactions of NO and O2 in Iron Enzymes : A Density Functional Theory Study

   Författare :Mattias Blomberg; Per Siegbahn; Adrian Mulholland; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; enzyme catalysis; redox reactions; cytochrome oxidase; nitric oxide reductase; hyponitrous acid anhydride; peroxynitrite; myoglobin; prostaglandin synthase; PGHS; NO; N2O; O2; CO; Chemical physics; Kemisk fysik;

   Sammanfattning : In the present thesis the density functional B3LYP has been used to study reactions of NO and O2 in redox active enzymes.Reduction of nitric oxide (NO) to nitrous oxide (N2O) is an important part in the bacterial energy conservation (denitrification). LÄS MER

3. 2. Mass spectrometric investigation of protein nitration in inflammation and neurodegeneration

   Författare :Henrik Ryberg; Göteborgs universitet; []
   Nyckelord :mass spectrometry; oxidative stress; nitrotyrosine; neurodegeneration; peroxynitrite; protein modification;

   Sammanfattning : The nitration of tyrosine seems to be very common in human diseases and at least forty different diseases have been reported to be associated with an increased nitration of proteins. The nitration of proteins results in a modification of tyrosine, 3-nitrotyrosine (3-NT), which is stable. LÄS MER

4. 3. The inter-and intramolecular selectivity of the carbonate radical anion in its reactions with lignin and carbohydrates

   Författare :Magnus Carlsson; Gábor Merényi; Clemens von Sonntag; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; nuclear chemistry; Kemi; Chemistry; Kemi;

   Sammanfattning : In the present thesis, the effects of the carbonate radical anion on lignin and cellulose were investigated. The carbonate radical has a rather high reactivity towards aromatic lignin constituents. It reacts especially fast with phenolates. All these reactions occur by way of electron transfer. LÄS MER

5. 4. Nitric oxide in tuberculosis and leprosy

   Författare :Thomas Schön; Gilla Kaplan; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is a global disease that kills about two million people each year. Leprosy is caused by Mycobacterium leprae, and primarily affects the skin and peripheral nervous system. LÄS MER

7. 5. Nitric oxide in brain contusion

   Författare :Caroline Gahm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Apoptosis; Colchicine; Dexamethasone; eNOS; human; immunohistochemistry; iNOS; L-NAME; L-NIL; neuronal degeneration; Nimodipine; nitric oxide; NO; nNOS; rat; SPBN; Tirilazad Mesylate; traumatic brain injury;

   Sammanfattning : Trauma to the brain is a leading cause of death and disability. The primary injury initiates a cascade of biochemical reactions in the brain that causes further neuronal damage, a process referred to as secondary brain injury. LÄS MER