Sökning: "graft-versus-host disease"

Visar resultat 16 - 20 av 72 avhandlingar innehållade orden graft-versus-host disease.

  1. 16. Langerhans cells in oral mucosa and skin. A functional and morphological study

    Författare :Bengt Hasséus; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Langerhans cells (LC) are a subpopulation of dendritic cells residing in skin and mucosal epi-thelium. LC capture antigens in the periphery and following migration to regional lymph nodes present peptides to T cells. LCs have a central role in initiating a T cell mediated immune re-sponse, both in health and disease. LÄS MER

  3. 17. Microarray gene expression in immunological conditions

    Författare :Abdulkareem Musa Heevy Al-Chaqmaqchi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The use of microarray techniques for gene expression analysis provides a global view of the transcriptional activity in a biological sample. In this thesis two conditions accompanied by disturbance in the immune system are addressed following the changes in gene expression. LÄS MER

  4. 18. Acute Lymphoblastic Leukaemia in Adult Patients : Studies of Prognostic Factors, Treatment Results and in vitro Cellular Drug Resistance

    Författare :Helene Hallböök; Bengt Smedmyr; Elin Lindhagen; Lorentz Brinch; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; acute lymphoblastic leukaemia; adult; adolescent; chemotherapy; stem cell transplantation; in vitro assay; imatinib; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Treatment results and clinical characteristics in adult acute lymphoblastic leukaemia (ALL) were evaluated regarding three issues: a new treatment with cytarabine up-front, stem cell transplantation and a comparison between adult and paediatric treatment protocols. All studies were conducted on a national basis. LÄS MER

  5. 19. T-cell Differentiation and Immunological Homeostasis in Lymphopenic and Kappa Light Chain Deficient Mice

    Författare :Frida Ekholm Pettersson; Fredrik Ivars; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; T cells; differentiation; homeostasis; cytokines; mice; SCID; κ-deficient; Biokemi; Biochemistry; Biokemi; immunologi; Immunology;

    Sammanfattning : T lymphocytes are primarily involved in adaptive, cell-mediated, immune reactions. In this thesis T cells were studied regarding central and peripheral differentiation and homeostatic mechanisms for maintanance of the immune repertoire.The influence by mature T cells on thymic development was studied in C. LÄS MER

  7. 20. B-cell immunity in patients with hematological malignancies and after stem cell transplantation : studies with special reference to tetanus and pneumococcal immunity

    Författare :Viera Hammarström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Treatment of malignancies with cytotoxic chemotherapy and/or bone marrow or stem cell transplantation also suppress the immune system which becomes incapable of controlling infections. Therefore infections can remain a serious problem for an extended period in these patients. LÄS MER