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Visar resultat 1 - 5 av 72 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Clinical aspects of chronic graft-versus-host disease

    Författare :Gabriel Afram; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic graft-versus-host disease (cGVHD) remains one of the most severe complications after allogeneic hematopoietic stem cell transplantation (HSCT), affecting both the quality of life and mortality of long-term survivors. Its impact on morbidity and mortality varies depending on the severity and number of organs involved, allowing classification into mild, moderate, and severe cGVHD according to the National Institute of Health criteria (NIH). LÄS MER

  3. 2. Graft-versus-Host Disease: Eosinophils, Chimerism and Clinical Features in Patients Undergoing Allogeneic Hematopoietic Stem Cell or Multivisceral Transplantation

    Författare :Julia Cromvik; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; graft-versus-host disease; eosinophilic granulocyte; intestinal transplantation; multivisceral transplantation; chimerism analysis;

    Sammanfattning : Abstract Graft-versus-host disease (GVHD) is a potentially severe complication that may develop after allogeneic hematopoietic stem cell transplantation (HSCT). It can also occur after transplantation with isolated intestinal grafts or after multivisceral transplantation (MVTX). GVHD is difficult to diagnose. LÄS MER

  4. 3. Graft-versus-host disease and treatment with mesenchymal stromal cells

    Författare :Lena von Bahr; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Graft-versus-host disease of both the acute (aGvHD) and chronic (cGvHD) variety remains a major cause of mortality and morbidity after allogeneic hematopoietic stem cell transplantation (HSCT). During the last 15 years, mesenchymal stromal cells (MSC) have been explored as a promising new treatment for aGvHD, but there are many questions to be answered in this young field. LÄS MER

  5. 4. Oral chronic Graft-versus-host disease : clinical and pathological staging

    Författare :Victor Tollemar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allogenic hematopoietic cell transplantation (HCT) is a curative treatment for many patients with immune- hematopoietic disorders, mainly hematopoietic cancers as leukaemia. Chronic Graft-versus-Host Disease (cGVHD) is a major long-term complication, associated with mortality and morbidity following allogenic HCT. LÄS MER

  7. 5. Molecular monitoring of acute graft-versus-host disease after allogenic stem cell transplantation

    Författare :Marie Jaksch; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Stem Cell Transplantation; Acute Graft-versus-host disease; FasL; Granzym B; Chemokine receptors; chimerism;

    Sammanfattning : Acute graft-versus-host disease (GVHD) remains a major barrier to the wider application of allogeneic stem cell transplantation (SCT) for a variety of diseases. GVHD occurs when the transplanted donor Tlymphocytes react to host antigens on antigen-presenting cells and attack host tissues. LÄS MER