Sökning: "graft-versus-host disease"

Visar resultat 6 - 10 av 72 avhandlingar innehållade orden graft-versus-host disease.

  1. 6. Stem cell transplantation : home care, graft-versus-host disease and costs

    Författare :Britt-Marie Svahn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Stem-cell transplantation; home-care; GVHD; costs;

    Sammanfattning : Allogeneic stem-cell transplantation (ASCT) is used to treat malignant and non-malignant diseases of the immunohematopoietic system. Results in terms of survival rate and less complications are continually improving due to better knowledge, supportive care, immunosuppression, new drugs against infections and HLA-typing techniques. LÄS MER

  3. 7. Female genital Graft-versus-Host Disease - Diagnosis, Treatment, Incidence, Long-term Prevalence, and Impact on Androgen Hormones and Sexual Function

    Författare :Eva Smith Knutsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allogeneic stem cell transplantation; chronic graft-versus-host disease; female genitalia; diagnostic; treatment; androgens in women; glucocorticosteroids; sexual dysfunction;

    Sammanfattning : ABSTRACT BACKGROUND. Chronic graft-versus-host disease (cGvHD) is the major cause of morbidity after allogeneic hematopoietic stem cell transplantation (alloSCT), and contributes to non-relapse mortality. Caused by donor cells, cGvHD is a multi-organ syndrome involving tissue inflammation and fibrosis. AIMS. LÄS MER

  4. 8. Immunobiology of graft versus host disease in chemotherapy based conditioning : new mouse model

    Författare :Behnam Sadeghi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Introduction: Graft versus host disease (GVHD) is a life threatening complication of allogeneic hematopoietic stem cell transplantation. The pathophysiology of GVHD is rather complex and several factors including; conditioning; MHC disparity and donor/host immune system influences both development and intensity of GVHD. LÄS MER

  5. 9. Effects on tumor immunity, liver, gut, lung and survival after cutaneous graft-versus-host disease regulated by photochemotherapy

    Författare :Gustav Nicolas Feldreich; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The present thesis describes the effect and timing of photochemotherapy in relation to the onset and severity of cutaneous graft-versus-host (GvHD) in relation to the survival and cure of patients. Leukemia is the most common childhood malignancy and an entity of cancer that is increasing in elderly. LÄS MER

  7. 10. Myofibroblasts and polyploid cells in the conjunctival surface after allogeneic hematopoietic stem cell transplantation

    Författare :David Hallberg; Göteborgs universitet; []
    Nyckelord :Myofibroblast; Polyploid; Allogeneic; Graft-versus-Host Disease;

    Sammanfattning : Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment modality for hematological malignancies, such as leukemia and lymphoma. However, a major complication of the procedure is that the immune effector cells in the graft may become activated towards the host´s healthy tissues, resulting in a condition called Graft-versus-Host Disease (GvHD). LÄS MER