Sökning: "genotype"
Visar resultat 21 - 25 av 697 avhandlingar innehållade ordet genotype.
21. Microenvironmental Impact on Tumour Cell Phenotype and Genotype in Adult and Paediatric Tumours
Sammanfattning : This thesis explores how the tumour microenvironment affects the phenotype and shapes the evolution of cancer cells. It encompasses four separate studies:First, we explored the effect of chemokines on the peritotumoral microenvironment of ovarian cancer. LÄS MER
22. Genotype/ phenotype correlation of two neuropsychiatric diseases. A genetic study of CDG1a and Rett syndrome
Sammanfattning : The aim of this thesis was to investigate the effects of mutations in the genes that cause the two neuropsychiatric diseases congenital disorder of glycosylation (CDG) type Ia and Rett syndrome. These two diseases affect children's central and peripheral nervous systems, causing mental retardation and neuronal impairment. LÄS MER
23. Exotoxins of Aggregatibacter actinomycetemcomitans and periodontal attachment loss in adolescents
Sammanfattning : Aggregatibacter actinomycetemcomitans is an oral bacterium that is mainly associated with aggressive forms of periodontitis, which most often starts at an early age. Amongst the virulence factors of A. LÄS MER
24. Genotype-phenotype studies in brain tumors
Sammanfattning : Meningioma and glioma are the most common primary brain tumors, but their etiologies are largely unknown. Although meningioma is usually benign, their intracranial location can lead to lethal consequences, and despite progress in surgery, radiotherapy, and chemotherapy the prognosis for patients with glioma remains poor. LÄS MER
25. Spatial and temporal ecology of oak-associated fungal communities
Sammanfattning : Plants host a large diversity of microorganisms, which includes fungi, bacteria and archaea. Among these, fungi are highly diverse, and known to play a vital role in plant health and in regulation of the essential ecosystem functions. LÄS MER