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Visar resultat 16 - 20 av 1809 avhandlingar som matchar ovanstående sökkriterier.
16. The Carboxyl Ester Lipase Gene. Organization, Evolution and Transcriptional Regulation in Exocrine Pancreas and Mammary Gland
Sammanfattning : The carboxyl ester lipase (CEL) is an important enzyme for the intestinal absorption of dietary lipids. In humans the gene is highly expressed in exocrine pancreas and in the lactating mammary gland. It is secreted in an inactive form and becomes activated by bile salts in the intestine. LÄS MER
17. The mitoribosome as a hub for integrating mitochondrial gene expression : Regulation of translation and early assembly of cytochrome b
Sammanfattning : The mitochondrial proteome is a mosaic of proteins from two different genetic systems. The majority of mitochondrial proteins are encoded in the nuclear genome and are synthesized in the cytosol before imported to mitochondria. LÄS MER
18. Organization and regulation of mitochondrial gene expression
Sammanfattning : Mitochondria possess their own genome, remnant of the ancestral eubacterial endosymbiont DNA. This mitochondrial genome encodes mostly few key subunits of the respiratory chain. In order to synthesize these few proteins, mitochondria contain a complete gene expression machinery. LÄS MER
19. Gene regulation by chromatin remodelling complexes : SWI/SNF complex in mRNA processing and B-WICH complex in ribosomal gene expression
Sammanfattning : The aim of this project is to investigate the roles of chromatin remodelling complexes in gene regulation. It is focused on two groups of chromatin complexes: the mammalian BRG1 and BRM SWI/SNF complexes and the ISWI-containing B-WICH complex.Study 1 investigates the role of SWI/SNF complexes in alternative splicing. LÄS MER
20. RNA-mediated gene expression regulation
Sammanfattning : The regulation of gene expression is a key mechanism that underlies all biological processes, from embryonic development to the onset and progression of various diseases, including cancer. A growing body of evidence places RNA molecules at the center of critical regulatory steps in gene expression. LÄS MER