Sökning: "gene expression evolution"

Visar resultat 1 - 5 av 211 avhandlingar innehållade orden gene expression evolution.

1. 1. Biased Evolution : Causes and Consequences

   Författare :Gerrit Brandis; Diarmaid Hughes; Erik Böttger; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolution; Codon usage bias; Post-transcriptional regulation; Recombination; Inversion; EF-Tu; Frameshift suppression; Antibiotic resistance; Rifampicin; Ciprofloxacin; Compensatory evolution; Drug efflux; RNA polymerase; DNA gyrase; Mikrobiologi; Microbiology;

   Sammanfattning : In evolution alternative genetic trajectories can potentially lead to similar phenotypic outcomes. However, certain trajectories are preferred over others. These preferences bias the genomes of living organisms and the underlying processes can be observed in ongoing evolution. LÄS MER

3. 2. Avian Genome Evolution - Gene Expression, Gene Divergence and Sexual Dimorphism

   Författare :Sara Naurin; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sex chromosome; avian genome evolution; gene expression; sexual dimorphism; Z chromosome;

   Sammanfattning : This study has focused on: (i) differences in how males and females use the genes in the genome, (ii) how sex chromosomes evolve and (iii) how the evolutionary rate of genes are affected by the chromosome on which they are located on and the gene expression level they experience. A large-scale microarray was developed for the zebra finch, Taeniopygia guttata and techniques were developed so that this microarray could also be used for wild passerine birds. LÄS MER

4. 3. Intrinsic disorder and tandem repeats - match made in evolution : Computational studies of molecular evolution

   Författare :Oxana Lundström; Arne Elofsson; Liberles-Siltberg Jessica; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; intrinsically disordered proteins IDPs ; tandem repeats; short tandem repeats STRs ; genetic variation; orphan proteins; GC content; human STR variation; colorectal cancer; gene expression; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

   Sammanfattning : Proteins are both the building blocks and workers of the cell, carrying out most of the important functions. For a long time, their structure has been regarded as the primary factor for their function, but intrinsically disordered proteins demonstrate an alternative to this paradigm. LÄS MER

5. 4. On the Evolution of the Avian Transcriptome

   Författare :Severin Uebbing; Hans Ellegren; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; evolution; gene expression; regulation; RNA-seq; transcriptomics; proteomics; sex chromosome; dosage compensation; divergence; ASE; birds; Ficedula; flycatcher; chicken; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : Change in gene expression is a powerful tool for evolution, because seemingly small expression changes can contribute important steps towards adaptation without necessarily affecting the whole organism. There is still much to learn about how gene expression evolves on genome- and population-wide levels, especially in non-model organisms. LÄS MER

7. 5. Exploring Brain Gene Expression i Animal Models of Behaviour

   Författare :Julia Lindberg; Elena Jazin; Peter Saetre; Jonathan Flint; Uppsala universitet; []
   Nyckelord :Biology; behavioural genetics; gene expression; brain; microarray analysis; domestication; animal model; haem; Canis familiaris; Vulpes vulpes; Mus musculus; Biologi;

   Sammanfattning : The genetic basis for behavioural traits is largely unknown. The overall aim of this thesis was to find genes with importance for behavioural traits related to fear and anxiety. Microarray analysis was used to screen expression profiles of brain regions important for emotional behaviour in dogs, wolves, foxes and mice. LÄS MER