Sökning: "sex chromosome"

Visar resultat 1 - 5 av 94 avhandlingar innehållade orden sex chromosome.

  1. 1. Genetic Sex Differences in Early Human Neuronal Development : An Investigation in Embryo Tissue and Embryonic Stem Cells

    Författare :Philipp Pottmeier; Elena Jazin; Armin Raznahan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex chromosome; gametolog; x y homolog; male; female; sex differences; sex bias; embryonic stem cells; neurodevelopment; neuronal differentiation; neural stem cells; genetics; neurodevelopmental disorders; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Neuroscience; Neurovetenskap; Medicinsk genetik; Medical Genetics;

    Sammanfattning : Sex differences in the human body affect many different organs and tissues, some of them have an effect on the human brain and its development. In the developing nervous system, sex differences can bias the number or functionality of neurons, glial cells or synapses. As a result, neural networks might develop with a sex-specific bias. LÄS MER

  3. 2. Evolution of sex chromosomes in Sylvioidea songbirds

    Författare :Hanna Sigeman; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sex chromosome; neo-sex chromosome; Birds; vertebrates; Genomics; Bioinformatics;

    Sammanfattning : Sex chromosomes were discovered more than 100 years ago. They have been studied intensely from a theoretical perspective since then, giving rise to a large body of testable predictions about their evolution from autosomes. LÄS MER

  4. 3. The genomic basis of the response to female-limited X-chromosome evolution

    Författare :Yesbol Manat; Evolutionär ekologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X chromosome; Sex chromosome; Drosophila melanogaster; Experimental evolution; sexual selection; intralocus sexual conflict;

    Sammanfattning : In this thesis, I attempted to achieve a better understanding of the nature of X-linked polymorphic loci using a female-limited X chromosome (FLX) experimental evolution in Drosophila melanogaster. I expected that expressing the evolved X chromosome will result in an increase in female fitness and a decrease in male fitness. LÄS MER

  5. 4. Sex Chromosome Evolution in a Hermaphrodite : Genetic and phenotypic relationships between sex roles

    Författare :Anna Nordén; Evolutionär ekologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Sex chromosome evolution; Hermaphrodite; Inter-sexual genetic correlation; Quantitative genetics; Macrostomum lignano; Experimental evolution; Sexual conflict;

    Sammanfattning : Sex chromosome evolution in a hermaphrodite ancestor starts with the establishment of a sex-determining region (SDR). Over time, sex-specific genes, and/or sexually antagonistic alleles will become linked to the SDR. LÄS MER

  7. 5. Splitting the sexes : The birth and senescence of sex chromosomes

    Författare :Aivars Cirulis; Evolutionär ekologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sex chromosome; Sexual conflict; Macrostomum lignano; Experimental evolution; Genomics of sex;

    Sammanfattning : The evolution of gonochorism from hermaphroditism can be gradual by increasing investment in one sex role while decreasing in the other, or rapid through the fixation of sex-role sterility mutations, eventually leading to the evolution of sex chromosomes. It is expected that the transition will involve a temporary state of gynodioecy or androdioecy as the mutations are not expected to take place at the same time. LÄS MER