Sökning: "functional coupling"
Visar resultat 1 - 5 av 244 avhandlingar innehållade orden functional coupling.
1. Functional association networks for disease gene prediction
Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER
2. Variations in Functional Lateralization
Sammanfattning : The general aim of this thesis was to study asymmetric activation of the neocortex in normal subjects, using the rCBF technique and different cognitive tasks. The aim was also to study individual and group variations of asymmetric activation, as well as factors pertaining to these variations. The thesis is based on four investigations. LÄS MER
3. Global functional association network inference and crosstalk analysis for pathway annotation
Sammanfattning : Cell functions are steered by complex interactions of gene products, like forming a temporary or stable complex, altering gene expression or catalyzing a reaction. Mapping these interactions is the key in understanding biological processes and therefore is the focus of numerous experiments and studies. LÄS MER
4. Inference of functional association networks and gene orthology
Sammanfattning : Most proteomics and genomics experiments are performed on a small set of well-studied model organisms and their results are generalized to other species. This is possible because all species are evolutionarily related. When transferring information across species, orthologs are the most likely candidates for functional equivalence. LÄS MER
5. Multi-functional Chromophores
Sammanfattning : As the push towards green energy become stronger, more efficient systems needs to be developed to compete with fossil fuel based systems. In modern Grätzel solar cells, most of the energy losses are inherited from the choice of chromophore and metal oxide surface. LÄS MER