Sökning: "network biology"

Visar resultat 1 - 5 av 284 avhandlingar innehållade orden network biology.

  1. 1. Single-cell RNA sequencing as a tool to study panarthropod evolution

    Författare :Brenda Irene Medina Jimenez; Ralf Janssen; Graham Budd; Tatjana Haitina; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Single-cell RNA sequencing; EvoDevo; gene expression; tissue dissociation; cell capture; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : Panarthropoda is a monophyletic group comprised of arthropods and lobopods, molting animals with a segmented body, paired appendages, dorsal brain, and ventral nerve cords. Evolutionary Developmental Biology (EvoDevo) is an interdisciplinary field that seeks to understand how changes in development form the basis for variations in morphology and phenotypic evolution, including the genetic network underlying these processes. LÄS MER

  3. 2. A systems biology understanding of protein constraints in the metabolism of budding yeasts

    Författare :Iván Domenzain Del Castillo Cerecer; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene regulation; omics analysis; enzyme capacity; metabolism; systems biology; stress adaptation; genome-scale modeling; metabolic engineering;

    Sammanfattning : Fermentation technologies, such as bread making and production of alcoholic beverages, have been crucial for development of humanity throughout history. Saccharomyces cerevisiae provides a natural platform for this, due to its capability to transform sugars into ethanol. LÄS MER

  4. 3. Systems Biology of Yeast Lipid Metabolism

    Författare :Pramote Chumnanpuen; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Transcriptome; Integrated analysis; Lipidome.; Inositol-choline; Opi1; Yeast lipid metabolism; high throughput techniques; Ino4; TORC1; Snf1; Ino2;

    Sammanfattning : Lipid metabolism plays an important role in the development of many different life-style related diseases, such as type 2 diabetes and atherosclerosis, and understanding the molecular mechanisms behind regulation of lipid biosynthesis and degradation may lead to development of new therapies. In this project we undertook a global study of lipid metabolism in the eukaryotic model organism Saccharomyces cerevisiae. LÄS MER

  5. 4. Long bone growth and evolution revealed by three-dimensional imaging

    Författare :Jordi Estefa; Sophie Sanchez; Per Ahlberg; Holly Woodward; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 3D histology; hematopoiesis; humerus; tetrapods; Biologi; Biology;

    Sammanfattning : Propagation phase-contrast synchrotron radiation microtomography is a non-destructive method used for studying histology in three dimensions (3D). Using it, the 3D organization of the diaphyseal cortical vascularization in the humerus of two seymouriamorphs was analyzed in this thesis. LÄS MER

  7. 5. Genetic mechanisms regulating proliferation and cell specification in the Drosophila embryonic CNS

    Författare :Shahrzad Bahrampour; Stefan Thor; Jan-Ingvar Jönsson; Simon Sprecher; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The central nervous system (CNS) consists of an enormous number of cells, and large cellular variance, integrated into an elaborate network. The CNS is the most complex animal organ, and therefore its establishment must be controlled by many different genetic programs. LÄS MER