Sökning: "network prediction"

Visar resultat 1 - 5 av 226 avhandlingar innehållade orden network prediction.

1. 1. Functional association networks for disease gene prediction

   Författare :Dimitri Guala; Erik L L Sonnhammer; Hjalmar Brismar; Yves Moreau; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER

3. 2. On protein structure, function and modularity from an evolutionary perspective

   Författare :Robert Pilstål; Björn Wallner; Maria Sunnerhagen; Mauno Vihinen; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; structure; biology; intrinsical; disorder; protein; sequence; evolution; mutation; epistasis; function; allostery; dynamics; simulation; prediction; graph; network; bioinformatik; struktur; biologi; strukturbiologi; intrinsiellt; oordnad; protein; sekvens; evolution; mutation; epistasis; funktion; allosteri; dynamik; simulation; prediktion; graf; nätverk;

   Sammanfattning : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. LÄS MER

4. 3. Short-Term Traffic Prediction in Large-Scale Urban Networks

   Författare :Matej Cebecauer; Erik Jenelius; Wilco Burghout; Balázs Kulcsár; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; travel time prediction; short-term travel time prediction; traffic prediction; clustering; partitioning; spatio-temporal partitioning; large-scale prediction; PPCA; 3D speed map; Transportvetenskap; Transport Science;

   Sammanfattning : City-wide travel time prediction in real-time is an important enabler for efficient use of the road network. It can be used in traveler information to enable more efficient routing of individual vehicles as well as decision support for traffic management applications such as directed information campaigns or incident management. LÄS MER

5. 4. Exploring the Boundaries of Gene Regulatory Network Inference

   Författare :Andreas Tjärnberg; Erik Sonnhammer; Richard Bonneau; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; GRN; gene regulatory network; network inference; signal to noise ratio; model selection; variable selection; data properties; reverse engineering; ordinary differential equations; gene networks; linear regression; lasso; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. LÄS MER

7. 5. Modeling prediction and pattern recognition in the early visual and olfactory systems

   Författare :Bernhard Kaplan; Lansner Anders; Fred Hamker; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; spiking neural networks; pattern recognition; self-organization; prediction; anticipation; visual system; olfactory system; modeling; Computer Science; Datalogi;

   Sammanfattning : Our senses are our mind's window to the outside world and determine how we perceive our environment.Sensory systems are complex multi-level systems that have to solve a multitude of tasks that allow us to understand our surroundings. LÄS MER