Sökning: "Yves Moreau"

Hittade 2 avhandlingar innehållade orden Yves Moreau.

  1. 1. Fusing Domain Knowledge with Data : Applications in Bioinformatics

    Författare :Claes Andersson; Jan Komorowski; Mats Gustafsson; Yves Moreau; Uppsala universitet; []
    Nyckelord :Bioinformatics; cell cycle; cancer chemotherapy; predictive tests; performance estimation; bioinformatics; Bioinformatik;

    Sammanfattning : Massively parallel measurement techniques can be used for generating hypotheses about the molecular underpinnings of a biological systems. This thesis investigates how domain knowledge can be fused to data from different sources in order to generate more sophisticated hypotheses and improved analyses. LÄS MER

  3. 2. Functional association networks for disease gene prediction

    Författare :Dimitri Guala; Erik L L Sonnhammer; Hjalmar Brismar; Yves Moreau; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER