Sökning: "biological networks"

Visar resultat 1 - 5 av 221 avhandlingar innehållade orden biological networks.

  1. 1. Functional association networks for disease gene prediction

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Dimitri Guala; Erik L L Sonnhammer; Hjalmar Brismar; Yves Moreau; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER

  2. 2. Dynamics in Random Boolean Networks

    Detta är en avhandling från Department of Theoretical Physics, Lund University

    Författare :Björn Samuelsson; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gravitation; relativity; quantum mechanics; biomathematics biometrics; Bioinformatik; medicinsk informatik; biomatematik; Mathematical logic; set theory; combinatories; Matematisk logik; Mathematical and general theoretical physics; kombinatorik; mängdlära; classical mechanics; Bioinformatics; tissue simulations; transcription networks; random graphs; random maps; nested canalyzing; canalyzing; genetic regulation; Kauffman networks; random Boolean networks; statistical physics; thermodynamics; medical informatics; Matematisk och allmän teoretisk fysik; klassisk mekanik; kvantmekanik; relativitet; termodynamik; statistisk fysik;

    Sammanfattning : There are many examples of complex networks in science. It can be genetic regulation in living cells, computers on the Internet, or social and economic networks. In this context, Boolean networks provide simplistic models that are relatively easy to handle using computer simulations and mathematical methods. LÄS MER

  3. 3. Reconstruction of Biological Networks for Integrative Analysis

    Detta är en avhandling från Department of Theoretical Physics, Lund University

    Författare :Tobias Österlund; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transcriptional regulation; : Biological networks; integrative analysis; protein secretion; genome-scale metabolic model;

    Sammanfattning : Biological systems can be very complex and consist of several thousand components that interact with each other in the cell. One of the goals of systems biology is to study biological systems from a systemic viewpoint in order to get an increased understanding of the behavior of the cell. LÄS MER

  4. 4. Global functional association network inference and crosstalk analysis for pathway annotation

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Christoph Ogris; Erik Sonnhammer; Alfonso Valencia; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological networks; genome wide functional association networks; global gene association networks; gene networks; protein networks; functional association; functional coupling; network biology pathway analysis; pathway annotation; pathway enrichment; network-based enrichment; enrichment; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : Cell functions are steered by complex interactions of gene products, like forming a temporary or stable complex, altering gene expression or catalyzing a reaction. Mapping these interactions is the key in understanding biological processes and therefore is the focus of numerous experiments and studies. LÄS MER

  5. 5. Multivariate Networks Visualization and Interaction Techniques

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Ilir Jusufi; Andreas Kerren; Jessie Kennedy; [2013]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Information Visualization; Multivariate Networks; Visual Analytics; Exploration; Interaction; Computer Science; Datavetenskap; Information and software visualization; Informations- och programvisualisering;

    Sammanfattning : As more and more data is created each day, researchers from different science domains are trying to make sense of it. A lot of this data, for example our connections to friends on different social networking websites, can be modeled as graphs, where the nodes are actors and the edges are relationships between them. LÄS MER