Sökning: "extracellular matrix"

Visar resultat 11 - 15 av 555 avhandlingar innehållade orden extracellular matrix.

1. 11. Pancreatic extracellular communication. Applications to beta cell cultures and islet amyloid polypeptide aggregation

   Författare :Diana Ribeiro; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in vitro pancreatic models; induced pluripotent stem cells; stem cell differentiation; insulin; 3D-culture; extracellular vesicles; glucose-stimulated insulin secretion; islet amyloid polypeptide; type 2 diabetes mellitus; extracellular matrix; adipose-derived stem cells; Diabetes mellitus; protein aggregation;

   Sammanfattning : Diabetes mellitus (DM) is a disease with epidemic proportions due to increased incidences worldwide, persistence of undiagnosed cases, uncontrolled forms of the disease, association with cardiovascular complications, and lack of definitive treatment options. In particular, type 2 DM (T2DM) is placing an enormous financial burden on worldwide healthcare systems that will increase in the futureThere is a need to develop physiological assay platforms that provide functionally relevant models of diabetes in order to accelerate the discovery of new treatments. LÄS MER

3. 12. Remodeling of airway epithelium and lung extracellular matrix in COPD and IPF

   Författare :Ulf Hedström; Lungbiologi; []
   Nyckelord :Chronic obstructive pulmonary disease; Idiopathic pulmonary fibrosis; Extracellular matrix; Epithelial cells; Remodeling;

   Sammanfattning : .... LÄS MER

4. 13. Extracellular matrix remodelling proteases in acute appendicitis and their impact on appendiceal perforation

   Författare :Anna Solberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; appendicitis; perforation; extracellular matrix; MMP-9; TIMP-1; uPA; PAI-1;

   Sammanfattning : Abstract Background Appendicitis is associated with varying degradation of extracellular matrix involved in tissue injury. The principal aim of this study was to investigate whether immunoreactive techniques could illustrate the course and severity of appendicitis and separate the different inflammatory grades, phlegmonous, gangrenous and perforated appendicitis, from each other and from uninflamed appendix. LÄS MER

5. 14. In vivo responses of neural progenitor cells to extracellular matrix signaling under pathological conditions

   Författare :Reza Motalleb; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptide Amphiphiles; Biomaterial; Tenascin - C; RGDS; RHAMM; Reactive Gliosis; Rostral Migratory Stream; Extracellular Matrix;

   Sammanfattning : The adult brain has an inherently low capacity for tissue regeneration, and neurons lost to disease or injuries are normally not replaced. This becomes especially apparent when stroke or brain trauma occurs. The discovery of neurogenesis and neural stem cells in the adult brain has opened up new avenues for treatment of the injured brain. LÄS MER

7. 15. Expression and localization of extracellular matrix proteins in rat skeletal development

   Författare :Zhenxin Shen; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BSP and osteoadherin.; COMP; chondroadherin; rat femoral head; Bone; extracellular matrix protein; cartilage; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

   Sammanfattning : Several novel matrix molecules of cartilage and bone have recently been identified and characterized. Studies of the maturation of the femoral head give clues as to the function of the novel matrix proteins. LÄS MER