Sökning: "extracellular matrix"

Visar resultat 31 - 35 av 555 avhandlingar innehållade orden extracellular matrix.

1. 31. Extracellular Matrix Remodelling-Proteoglycan and collagen turnover in arthritis

   Författare :Anette Bjärdahlen; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arthritis; collagen; cartilage; myofibroblasts; pannus; proteoglycan; Skeleton; muscle system; rheumatology locomotion; reumatologi; Skelett; muskelsystem;

   Sammanfattning : Rheumatoid arthritis is a chronic, inflammatory and systemic disease characterised by joint destruction and pannus formation. To enlarge the understanding how pannus and granulation tissue are formed two animal models were used; one using cartilage wrapped in cotton and implanted into a rat air pouch (AP) and one where mBSA induced arthritis (AIA) was performed. LÄS MER

3. 32. Studies on the extracellular matrix of the dysfunctional pelvic floor

   Författare :Marie Westergren Söderberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Pelvic floor; pelvic organ prolapse; stress urinary incontinence; extracellular matrix; collagen; SLRPs; decorin; lumican; fibromodulin; elastin associated proteins; fibrillin-1; fibulin-5; sex steroid hormone receptors; ER; PR; AR;

   Sammanfattning : Objective: Pelvic floor dysfunction cause impaired quality of life of many women and is one of the most common reasons for gynaecological surgery on benign indications. Little is known about the pelvic floor extracellular matrix as a pre-requisite for mechanical sustainability through vaginal delivery, age and hormonal changes. LÄS MER

4. 33. Granulocyte Adhesion to Matrix Proteins and the Effect on the Release of Granule Proteins : Development of a Simple Method and its Application in Experimental and Clinical Studies

   Författare :Xiaoyan Xu; Joachim Lundahl; Uppsala universitet; []
   Nyckelord :Medical sciences; Eosinophils; Neutrophils; Adhesion; Release of ECP; Extracellular matrix proteins; Granulocytes; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

   Sammanfattning : Granulocyte adhesion and release of their granule proteins are key steps during selective accumulation of a certain cell to an inflammatory site. Eosinophils are specifically recruited to sites of allergic inflammation and parasitic infection, whereas neutrophil influx predominates in bacterial infection and rheumatoid arthritis. LÄS MER

5. 34. Lipoprotein(a) in cardiovascular disease

   Författare :Ulf Lundstam; Göteborgs universitet; []
   Nyckelord :atherosclerosis; Lipoprotein a ; LDL; extracellular matrix; women;

   Sammanfattning : The atherosclerotic process is continuous and starts early in life. Risk factors for atherosclerosis include hyperlipidemia, hypertension, smoking and diabetes mellitus. Fatty streaks characterised by lipid-laden macrophages are early signs of atherosclerosis. LÄS MER

7. 35. The role of leucine-rich repeat glycoproteins/proteoglycans in the assembly of collagen matrices

   Författare :Liz Svensson; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; Skelett; decorin; Collagen; fibromodulin; extracellular matrix; lumican; collagen fibrillogenesis; Skeleton; rheumatology locomotion; muscle system; Biochemistry; Biokemi; Metabolism;

   Sammanfattning : The properties of different connective tissues depend on the synthesis and assembly of macromolecular structures composed of collagen and other extracellular matrix components. Mechanisms modulating these events play important roles in the formation of a functional tissue. LÄS MER