Sökning: "Tenascin - C"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Tenascin - C.

  1. 1. Complex Formation in the Extra Cellular Matrix- Structural Study of CTLD of Agrrecan, Tenascin-R and Chondroadherin

    Författare :Anna Pramhed; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aggrecan; ECM; fibulin; structure; tenascin; CHAD; chondroadherin; X-ray; crystallography; calcium; CTLD; C-type lectin; fibronectin; FnIII; LRR; epidermal growth factor; leucine-rich repeat; matrix; EGF; cbEGF;

    Sammanfattning : The cells of higher organisms exist in a complex protein network, the extracellular matrix (ECM), which has a wide variety of different components such as glycoproteins, proteoglycans and carbohydrates. As well as being the physical scaffold on which the cells are dependent for their positioning and mobility, the ECM exercises control over the cells, and changes in the matrix will affect the adhesion, proliferation and differentiation properties of these cells. LÄS MER

  3. 2. In vivo responses of neural progenitor cells to extracellular matrix signaling under pathological conditions

    Författare :Reza Motalleb; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptide Amphiphiles; Biomaterial; Tenascin - C; RGDS; RHAMM; Reactive Gliosis; Rostral Migratory Stream; Extracellular Matrix;

    Sammanfattning : The adult brain has an inherently low capacity for tissue regeneration, and neurons lost to disease or injuries are normally not replaced. This becomes especially apparent when stroke or brain trauma occurs. The discovery of neurogenesis and neural stem cells in the adult brain has opened up new avenues for treatment of the injured brain. LÄS MER

  4. 3. Stromal components and micro-RNAs as biomarkers in pancreatic cancer

    Författare :Oskar Franklin; Malin Sund; Daniel Öhlund; Ola Billing; Marco Del Chiaro; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; stroma; basement membrane; tumour markers; type IV collagen; endostatin; osteopontin; tenascin c; hyaluronan; CD44; micro-RNA; kirurgi; Surgery;

    Sammanfattning : Background Pancreatic ductal adenocarcinoma (PDAC) patients have the poorest 5-year survival rates of all cancer forms. It is difficult to diagnose at early disease stages, tumour relapse after surgery is common, and current chemotherapies are ineffective. LÄS MER

  5. 4. The extracellular matrix protein tenascin-C in development and in experimental cancer

    Författare :Jan F. Talts; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  7. 5. Factors influencing the turnover of olfactory receptor neurons

    Författare :Maja-Lena Deckner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :immunohistochemistry; in situ hybridization; rat; olfactory bulb; olfactory epithelium; axotomy; regeneration; apoptosis; BBB; VEGF; blood vessels; trophic factor; BDNF; trkB; tenascin;

    Sammanfattning : The olfactory system has a striking capacity for neuronal plasticity throughout life and the olfactory epithelium is able to generate both neuronal and non-neuronal cells in the normal adult animal as well as after experimental injury. In contrast to primary sensory neurons, olfactory axons are able to cross the border between the PNS and CNS in the olfactory bulb after transection in the adult animal. LÄS MER