Sökning: "TIMP-1"

Visar resultat 1 - 5 av 45 avhandlingar innehållade ordet TIMP-1.

  1. 1. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

    Författare :Marie Klintman; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; predictive marker; resistance; prognostic factor; proliferation; prospective; TIMP-1; Ki67; S-phase; MAI; PPH3; cyclin B1; cyclin A; node-negative; validation;

    Sammanfattning : Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. LÄS MER

  3. 2. Extracellular matrix remodelling proteases in acute appendicitis and their impact on appendiceal perforation

    Författare :Anna Solberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; appendicitis; perforation; extracellular matrix; MMP-9; TIMP-1; uPA; PAI-1;

    Sammanfattning : Abstract Background Appendicitis is associated with varying degradation of extracellular matrix involved in tissue injury. The principal aim of this study was to investigate whether immunoreactive techniques could illustrate the course and severity of appendicitis and separate the different inflammatory grades, phlegmonous, gangrenous and perforated appendicitis, from each other and from uninflamed appendix. LÄS MER

  4. 3. Migration on extracellular matrix surface and infiltration into matrix - two distinguishable activities of human T cells

    Författare :Jyrki Ivanoff; Karl-Gösta Sundqvist; Joachim Lundahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; extracellular matrix; fibronectin; collagen type IV; laminin; neuropeptide; chemokine; TIMP-1; MMP-9; T cells; Migration; Immunologi; Immunology; Immunologi; Clinical Immunology; klinisk immunologi;

    Sammanfattning : Migration of T-lymphocytes on a surface coated with extracellular matrix (ECM) components (two-dimensional (2-D) migration) and migration (infiltration) into a matrix (Three-dimesional (3-D) migration) are complex events and the underlying mechanisms are not yet fully understood. Here 2-D and 3-D migration were studied by use of seven leukemic T-cell lines representing discrete differentiation stages, a non-leukemic T-cell clone, and normal peripheral blood T cells. LÄS MER

  5. 4. Rectal Cancer - Tumor Biology and Prognostic Markers

    Författare :Eva Fernebro; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prognostic markers; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; immunohistochemistry IHC ; chromosomal instability CIN ; microsatellite instability MSI ; tissue microarray TMA ; tissue inhibitor of metalloproteinase 1 TIMP-1 ; Rectal cancer; soluble urokinase plasminogen activator receptor suPAR ;

    Sammanfattning : Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. LÄS MER

  7. 5. Urinary tract infection and renal scarring

    Författare :Milan Chromek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :urinary tract infection; renal scarring; cathelicidin; LL-3 7; NIMP-9; TIMP-1;

    Sammanfattning : Urinary tract infection (UTI) is the most common bacterial infection. Although most patients with UTI have a good prognosis, there is a risk of serious complications in a group of them. LÄS MER