Sökning: "Reactive Gliosis"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden Reactive Gliosis.

  1. 1. Astrocytes, reactive gliosis and CNS regeneration

    Författare :Ulrika Wilhelmsson; Göteborgs universitet; []
    Nyckelord :CNS regeneration; astrocytes; reactive gliosis; intermediate filaments;

    Sammanfattning : The regenerative capacity in the adult central nervous system (CNS) is very limited, and the glial cells have been implicated in the inhibition of CNS regeneration. In essentially all CNS pathologies, astrocytes are activated and this process is known as reactive gliosis. LÄS MER

  3. 2. Reactive gliosis in the injured brain: The effect of cell communication and Nrf2-mediated cellular defence

    Författare :Heléne Andersson; Göteborgs universitet; []
    Nyckelord :Keywords: astrocyte; gap junction; Hmox1; microglia; Nrf2; Nqo1; oxidative stress; reactive gliosis;

    Sammanfattning : Stroke and other brain injuries trigger an extensive glial cell response referred to as reactive gliosis. Reactive gliosis is characterized by hypertrophic and proliferating astrocytes, proliferating microglia and NG2-positive cells, which eventually form a bordering glial scar around the damaged area. LÄS MER

  4. 3. The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma

    Författare :Lizhen Li; Göteborgs universitet; []
    Nyckelord :astrocytes; intermediate filaments; GFAP; vimentin; reactive gliosis; brain ischemia; neurotrauma;

    Sammanfattning : Astrocytes are the most abundant cell type in the central nervous system (CNS) and increasing evidence now suggests that they play an active role in various brain functions. Astrocytes are involved in the induction and maintenance of the blood brain barrier, as well as the induction and stabilization of neuronal synapses. LÄS MER

  5. 4. Role of intermediate filaments and expression of GFAP and S-100 in astrocytes

    Författare :Mei Ding; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Gliosis; Kainic acid; Transgenic mouse; S-100; GFAP; Vimentin; RVD regulatory volume decrease ; Taurine; Glutamine; Ascorbate; Glucose;

    Sammanfattning : Astrocytes participate in a variety of important physiologic and pathologic processes in the central nervous system (CNS). One of the most remarkable characteristics of astrocytes is their vigorous response to CNS injuries. LÄS MER

  7. 5. Inflammation and Cell Profileration Following Perinatal Brain Injury

    Författare :Katarina Järlestedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypoxia-ischemia; immature brain; reactive gliosis; complement system; C3a; fear conditioning; lipopolysaccharide; inflammation;

    Sammanfattning : Inflammation plays an important role in cerebral ischemic injury in the immature brain. The aim of the thesis was to investigate (1) the role of astrocyte activation and reactive gliosis in neonatal hypoxic-ischemic (HI) brain injury, (2) the role of complement derived peptide C3a in neonatal HI brain injury, (3) the effect of neonatal HI brain injury on fear learning and behaviour, (4) the effects of lipopolysaccharide (LPS) induced systemic inflammation on cell proliferation in the developing brain. LÄS MER