Sökning: "drug use"

Visar resultat 1 - 5 av 899 avhandlingar innehållade orden drug use.

  1. 1. Characterization of parameters influencing intracellular bioavailability and prediction of intracellular drug exposure

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Andrea Treyer; Uppsala universitet.; [2019]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular drug bioavailability; unbound drug concentration; drug disposition; ADME; drug transport; drug metabolism membrane partitioning; phospholipid; drug-drug interaction; antisense oligonucleotide; cell-penetrating peptide; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : This thesis work investigates factors influencing intracellular drug disposition. An experimental method for measurement of intracellular bioavailability (Fic), was used throughout. Fic is defined as the ratio between the unbound drug concentration inside the cell and the compound concentration in the cell exterior. LÄS MER

  2. 2. Psychoactive prescription drug use disorders, misuse and abuse Pharmacoepidemiological aspects

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Micaela Tjäderborn; Linköpings universitet.; Linköpings universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychoactive prescription drugs; psychotropic drugs; prescription drug use disorders; prescription drug misuse; abuse; pharmacovigilance; drug utilization; pharmacoepidemiology;

    Sammanfattning : Background: There is a widespread and increasing use of psychoactive prescription drugs, such as opioid analgesics, anxiolytics, hypnotics and anti-epileptics, but their use is associated with a risk of drug use disorder, misuse and abuse. Today, these are globally recognized and emerging public health concerns. LÄS MER

  3. 3. Hazards of Drug Therapy On the Management of Adverse Drug Reactions: From Signal Detection and Evaluation to Risk Minimization

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Karin Hedenmalm; Uppsala universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting systems; drug regulation; pharmacovigilance; incidence; Farmakologi; MEDICINE Physiology and pharmacology Pharmacological research; MEDICIN Fysiologi och farmakologi Farmakologisk forskning;

    Sammanfattning : Spontaneous reporting systems (SRSs) for adverse drug reactions (ADRs) have been developed as a result of the thalidomide disaster, whereby thousands of children world-wide were born with birth defects. The Swedish Adverse Drug Reactions Advisory Committee was established in 1965. LÄS MER

  4. 4. Skapande av femininitet : om kvinnor i missbrukarbehandling

    Detta är en avhandling från Leili Laanemets, Socialhögskolan, Box 23, 221 00 Lund

    Författare :Leili Laanemets; Lunds universitet.; Lund University.; [2002]
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; client.; drug use; drug abuse; drugs; alcohol; drug treatment; addiction treatment; motherhood; sex; gender; femininity; women; Social problems and welfare; national insurance; Sociala problem; social välfärd; socialförsäkring;

    Sammanfattning : Popular Abstract in Swedish Skapande av femininitet, om kvinnor i missbrukarbehandling Denna avhandling handlar om kvinnor i missbrukarbehandling och deras beskrivningar av sig själva som kvinnor, den s.k. femininitetsprocessen. LÄS MER

  5. 5. Drug Eluting Hydrogels Design, Synthesis and Evaluation

    Detta är en avhandling från University of Cape Town

    Författare :Lage Ahrenstedt; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drug delivery; PEGylation; Rapamycin; Dexamethasone; Controlled release; Hydrogels; Slow release;

    Sammanfattning : Hydrogels have successfully proved themselves useful for drug delivery applications and several delivery routes have been developed over the years. The particular interest in this work was to design, synthesise and evaluate in situ forming drug eluting hydrogels, which have the potential to ameliorate the healing of cardiovascular diseases. LÄS MER