Sökning: "co-expression"
Visar resultat 6 - 10 av 100 avhandlingar innehållade ordet co-expression.
6. Functional domains in the Alzheimer's disease-associated presenilin 1 protein
Sammanfattning : Alzheimer's disease (AD), the most common cause of dementia, is neuropathologically characterized by the presence of neurofibrillary tangles and amyloid plaques in the brain. Amyloid plaques are extracellular deposits primarily composed of the amyloid beta-peptide (Abeta). LÄS MER
7. Imaging serotonin and dopamine transporters in social anxiety disorder : Characterization, treatment and expectancy effects
Sammanfattning : The monoamines serotonin and dopamine are likely to be involved in the pathophysiology of social anxiety and other affective disorders, but their respective contributions and putative interactions in the causes and cures of these disorders are still not well understood. It is also largely unknown if and how expectations of treatment success affect brain neurochemistry and neural activations, and if expectations interact with antidepressants like selective serotonin reuptake inhibitors (SSRIs). LÄS MER
8. Targeting Mycobacterium tuberculosis Proteins: Structure and Function Studies of Five Essential Proteins
Sammanfattning : This thesis describes the target selection, cloning, expression, purification, crystallization, structure and biochemical characterization of five essential Mycobacterium tuberculosis (Mtb) proteins. The search for drugs against the causal agent of tuberculosis is urgently needed and the targeting of essential genes is necessary to fulfill this goal. LÄS MER
9. The influence of lysozyme and oligothiophenes on amyloid-β toxicity in models of Alzheimer’s disease
Sammanfattning : Alzheimer’s disease (AD) is a neurodegenerative disease and the most common cause of dementia worldwide. Apart from dominantly inherited mutations, age is the major risk factor and as life expectancy increases the prevalence for AD escalates dramatically. LÄS MER
10. Studies of LRIG1 and the ERBB receptor family in breast and colorectal cancer
Sammanfattning : The LRIG1 gene (leucine-rich repeats and immunoglobulin like domains-1) at chromosome 3p14 is a proposed tumour suppressor gene whose gene product negatively regulates various receptor tyrosine kinases. This function has been the basis for classifying LRIG1 as a potential tumour suppressor gene (TSG). LÄS MER
