Sökning: "Rv1284"

Hittade 2 avhandlingar innehållade ordet Rv1284.

  1. 1. Targeting Mycobacterium tuberculosis Proteins: Structure and Function Studies of Five Essential Proteins

    Författare :Adrian Suarez Covarrubias; Sherry Mowbray; Torsten Unge; Pedro Alzari; Uppsala universitet; []
    Nyckelord :Cell and molecular biology; carbonic anhydrase; threonine synthase; FAS II; Rv0636; Rv1284; Rv1295; Rv3588c; Rv3778c; X-ray crystallography; Cell- och molekylärbiologi; Mycobacterium tuberculosis;

    Sammanfattning : This thesis describes the target selection, cloning, expression, purification, crystallization, structure and biochemical characterization of five essential Mycobacterium tuberculosis (Mtb) proteins. The search for drugs against the causal agent of tuberculosis is urgently needed and the targeting of essential genes is necessary to fulfill this goal. LÄS MER

  3. 2. Evaluation of immunological markers for the diagnosis of active and latent tuberculosis

    Författare :Emilie Wahren Borgström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tuberculosis (TB) is the single deadliest infectious disease in the world and around one fourth of the global population is estimated to be latently infected with Mycobacterium tuberculosis (Mtb). The World Health Organization (WHO) targets reduction of mortality by 95% and incidence rate by 90% by year 2035. LÄS MER