Sökning: "calcium channel"

Visar resultat 26 - 30 av 121 avhandlingar innehållade orden calcium channel.

  1. 26. Calcium signaling and network activity : mathematical modeling and molecular mechanisms

    Författare :Erik Smedler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The calcium (Ca2+) ion is a versatile second messenger present in all cells. It is involved in such diverse processes as cell division, differentiation, vesicle transport and muscle contraction. Its widespread applicability is partially explained by its wide temporal and spatial dynamics. LÄS MER

  3. 27. Cell responses in infected and cystic fibrosis respiratory epithelium

    Författare :Rashida Hussain; Godfried M . Roomans; Maria Björkqvist; Ferenc Karpati; Hans Kollberg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelial cells; cystic fibrosis; bacterial infection; CFTR; ENaC; chloride transport; intracellular calcium; P. aeruginosa internalization; Biomedicin; Biomedicine;

    Sammanfattning : Respiratory Epithelium. Örebro Studies in Medicine 99. Cystic fibrosis (CF) is caused by a mutation in a cAMP-activated chloride (Cl-) channel (CFTR). Mortality and morbidity in CF is mainly due to the deregulated responses of the airway epithelial cells. LÄS MER

  4. 28. The Best Leading Role for Maintaining Normal β-cell Function Goes to MafA and Voltage-gated Calcium Channel Subunit γ4

    Författare :Cheng Luan; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; insulin secretion; pancreatic islet; MafA; CaVγ4; CaV channels; β-cell function; dedifferentiation; transcription factor; patch clamp; Ca2 signaling; cholinergic nicotinic receptor; ChrnB4; GDF11; aging; islet inflammation; maturation;

    Sammanfattning : .... LÄS MER

  5. 29. Studies on molecular mechanisms in calcium signaling and cellular energy consumption

    Författare :Kalaiselvan Krishnan; Hjalmar Brismar; Anders Tengholm; KTH; []
    Nyckelord :ca2 signaling; ATP; PercevalHR; NKA; diabetes; Angiotensin; Biological Physics; Biologisk fysik;

    Sammanfattning : Ion signaling plays fundamental role in cell survival. Na+ and Ca2+ are critical players in ion signaling. Cells spend the major amount of energy to maintain and regulate Na+ and Ca2+ gradients across the cell membrane. Any disruption in cellular energy consumption by plasma membrane ATPases affects ion signaling and vice versa. LÄS MER

  7. 30. Calcium dynamics and vesicle-release proteins in a prion-infected neuronal cell line

    Författare :Malin Sandberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Prion; Scrapie; Voltage-gated N-type calcium channels; SNARE proteins; Exocytosis; Long-term depolarization;

    Sammanfattning : The prion particle, PrPSc, is an infectious, misfolded form of the cellular prion protein, PrPC that is expressed at high levels in the central nervous system. Prions cause neurodegenerative diseases with clinical signs including dementia, ataxia and myoclonus. These diseases cause characteristic electroencephalographic changes. LÄS MER