Sökning: "Kalaiselvan Krishnan"

Hittade 2 avhandlingar innehållade orden Kalaiselvan Krishnan.

1. 1. Molecular mechanisms involved in the generation of calcium signals in insulin secreting cells

   Författare :Kalaiselvan Krishnan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Intracellular Ca 2+ regulates diverse cellular functions in almost all the cells. In the pancreatic ß-cells, Ca 2+ signals are critical for insulin secretion. An increase in the cytoplasmic free Ca 2+ concentration ([Ca 2+ ]i) triggers insulin secretion. LÄS MER

3. 2. Studies on molecular mechanisms in calcium signaling and cellular energy consumption

   Författare :Kalaiselvan Krishnan; Hjalmar Brismar; Anders Tengholm; KTH; []
   Nyckelord :ca2 signaling; ATP; PercevalHR; NKA; diabetes; Angiotensin; Biological Physics; Biologisk fysik;

   Sammanfattning : Ion signaling plays fundamental role in cell survival. Na+ and Ca2+ are critical players in ion signaling. Cells spend the major amount of energy to maintain and regulate Na+ and Ca2+ gradients across the cell membrane. Any disruption in cellular energy consumption by plasma membrane ATPases affects ion signaling and vice versa. LÄS MER