Sökning: "cholinergic nicotinic receptor"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden cholinergic nicotinic receptor.

  1. 1. Spinal Acetylcholine Release : Mechanisms and Receptor Involvement

    Författare :Mahinda Kommalage; Urban Höglund; Ernst Brodin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; acetylcholine release; spinal antinociception; nicotinic receptor; serotonin; GABA; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Impulses coming from peripheries are modified in the spinal cord and transmitted to the brain. Several neurotransmitters have been involved in the processing of impulses in the spinal dorsal horn. Acetylcholine (ACh) is one of many neurotransmitters involved in the regulation of nociception in the spinal cord. LÄS MER

  3. 2. Development of nicotinic receptor ligands for positron emission tomography - from in vitro to in vivo : Binding studies of neuronal nicotinic acetylcholine receptors using different ³H-, ¹1C- and `6Br - labeled ligands

    Författare :Wiebke Sihver; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; nicotinic acetylcholine receptor; PET-ligand; in vitro; in vivo; Alzheimer s disease; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in central processes, such as cognitive functionand memory, and play a critical role in neuropathological changes in Alzheimer's disease (AD). The in vivocharacterization of nAChRs by positron emission tomography (PET) may increase our understanding of thefunctional implications of these receptors in AD and their early changes during this disease. LÄS MER

  4. 3. Muscarinic Receptors in the Urinary Bladder - The role of the urothelium regarding cholinergic and nitrergic effects in inflammation

    Författare :Michael Andersson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; urinary bladder; inflammation; cyclophosphamide-induced cystitis; muscarinic receptor; urothelium; nitric oxide; M5 receptor; rat; proliferation; micturition;

    Sammanfattning : Inflammation alters the functional properties of the urinary bladder. Interstitial cystitis (IC) is a chronic inflammatory syndrome in man that is characterized by urgency, frequency and visceral pain. LÄS MER

  5. 4. Cell membrane involving phenomena in two cholinergic systems : endocytosis in denervated striated muscle and nicotinic acetylcholine/P2-purinergic receptor interactions in mammalian inner ear

    Författare :Grace Kerali Lawoko; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  7. 5. The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury

    Författare :Maria Hammarlund; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha 7 nicotinic acetylcholine receptor; inflammation; brain injury; CHRNA7; CHRFAM7A; stroke; hypoxia ischemia; neonatal encephalopathy; human; PBMC;

    Sammanfattning : The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common component in the pathology of many diseases and injuries, including brain damage. LÄS MER