Sökning: "CaVγ4"

Hittade 2 avhandlingar innehållade ordet CaVγ4.

1. 1. The Best Leading Role for Maintaining Normal β-cell Function Goes to MafA and Voltage-gated Calcium Channel Subunit γ4

   Författare :Cheng Luan; Diabetes - öpatofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; insulin secretion; pancreatic islet; MafA; CaVγ4; CaV channels; β-cell function; dedifferentiation; transcription factor; patch clamp; Ca2 signaling; cholinergic nicotinic receptor; ChrnB4; GDF11; aging; islet inflammation; maturation;

   Sammanfattning : .... LÄS MER

3. 2. Regulation of insulin secretion in diabetes: Molecular mechanism and applications

   Författare :Rui Wu; Diabetes - öpatofysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin production secretion; CaV channels; DEGs; aging; magnetic field;

   Sammanfattning : Diabetes is a highly ageing-related disease manifesting with a deteriorated capacity of insulin secretion and uncontrolled blood glucose-raising, hyperglycemia. In this thesis, we aim to explore the underlying roles of CaV channels and aging-associated genetic changes in the development of Type 2 diabetes (T2D). LÄS MER