Sökning: "bisphenols"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet bisphenols.

  1. 1. Computational methods for assessing chemical risk : focusing on toxicokinetic modelling in zebrafish (danio rerio)

    Författare :Ioana C. Chelcea; Patrik L. Andersson; Timo Hamers; Jessica Legradi; Stefan Örn; Carolina Vogs; Nynke Kramer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PBTK; Toxicokinetics; Endocrine disruptors; bisphenols; zebrafish; embryo; Toxicology; toxikologi;

    Sammanfattning : New chemicals are constantly produced and large data gaps exist on hazards of currently used industrial chemicals, stressing the need for rapid, ethically sound and cost-efficient hazard assessment methods. Traditional methods for effect assessment based on animal testing, do not meet these requirements and thus the toxicology field has been moving towards the development of new approach methodologies which include in vitro approaches but also computational methods. LÄS MER

  3. 2. Development of in silico methods to aid chemical risk assessment : focusing on kinetic interactions in mixtures

    Författare :Elena Golosovskaia; Patrik L. Andersson; Stefan Örn; Patrik Rydén; Ester Papa; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; QSAR; physiologically based kinetic; PBK; zebrafish; ADME; mixture; bisphenols; PFAS; toxicokinetics; environmental science; miljövetenskap; Toxicology; toxikologi;

    Sammanfattning : The environment and biota are constantly exposed to numerous chemicals through contaminated food, soil, water, and air. These chemicals can be taken up and distributed to reach sensitive tissues where they may cause various effects. Many of these chemicals lack data on their environmental and human health effects. LÄS MER

  4. 3. Optimizing nontarget workflows for identification of organic contaminants in various matrices

    Författare :Florian Dubocq; Anna Kärrman; Thanh Wang; Juliane Hollender; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nontarget analysis; workflow optimization; statistical analysis; mass defect plot; organic contaminants; environmental matrices;

    Sammanfattning : Since year 2000, production of chemicals around the world has more than doubled. Chemicals are used in many and diverse applications in our everyday life and even if their properties are useful, some can have a negative impact on environment and humans. LÄS MER

  5. 4. Early life environmental exposures and children's growth : A longitudinal study evaluating prenatal exposure for endocrine disrupting chemicals and nutrition in relation to children's growth up to seven years of age

    Författare :Katherine Svensson; Carl-Gustaf Bornehag; Sverre Wikström; Chris Gennings; Alicja Wolk; Marie Löf; Karlstads universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrine disrupting chemicals; EDC; Nutrition; Pregnancy; Children; Growth; Birthweight; Body composition; Body Fat; BMI; Overweight; Public Health Science; Folkhälsovetenskap;

    Sammanfattning : Endocrine disrupting chemicals (EDCs) have the potential to disrupt the endocrine system in humans and animals with importance for health and development. Additionally, optimal nutrition during pregnancy is critical for fetal growth and pregnancy outcomes. LÄS MER

  7. 5. Characterizing chemical exposure : focus on children's environment

    Författare :Kristin Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Children are constantly exposed to chemicals in food, water, dust, air and consumer products. Compared to adults, children often have a higher exposure to chemicals due to physical and behavioural factors. Because of their unique exposure patterns, exposure assessments in adults are not directly transferrable to children. LÄS MER