Sökning: "beta-lactamase"

Visar resultat 21 - 25 av 30 avhandlingar innehållade ordet beta-lactamase.

  1. 21. Epidemiology of ESBL-producing E. coli with special reference to outbreak detection

    Författare :Lisa Helldal; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E. coli; epidemiology; surveillance;

    Sammanfattning : Multidrug resistant bacteria, particularly extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (EPE), are becoming a major health concern. ESBL-producing Escherichia coli (ESBL-E. coli) is the most prevalent type. ESBL-genes are carried on plasmids, often by bacteria belonging to clones with properties that facilitate transmission. LÄS MER

  2. 22. Carbon monoxide and nitric oxide as antimicrobial agents : focus on ESBL-producing uropathogenic E.coli

    Författare :Charlotte Sahlberg Bang; Katarina Persson; Bo Söderquist; Annelie Brauner; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biofilm; carbon monoxide; CORM-2; DETA NO; extendedspectrum beta-lactamases; nitric oxide; urinary tract infection; uropathogenic Escherichia coli; Biomedicin; Biomedicine;

    Sammanfattning : Urinary tract infections (UTI) are common in humans and most often caused by uropathogenic Escherichia coli (E. coli). Extended-spectrum beta-lactamase (ESBL)-producing E. coli are increasing worldwide and they are frequently multidrug-resistant with limited treatment options. LÄS MER

  3. 23. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

    Författare :Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

    Sammanfattning : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. LÄS MER

  4. 24. Antibiotic resistance gone wild : A One Health perspective on carriage, selection and transmission of Extended-Spectrum Cephalosporinase- and Carbapenemase-producing Enterobacteriaceae

    Författare :Clara Atterby; Josef D. Järhult; Nicola Williams; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; E. coli; K. pneumoniae; ESBL; AmpC; Carbapenemase; ciprofloxacin resistance; colistin resistance; rural; wildlife; birds; sub-MIC; MSC; Cambodia; environment; epidemiology; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Antibiotics have saved millions of lives since they came into clinical use during the Second World War in the 1940s. Today, our effective use of antibiotics is under great threat due to emerging antibiotic resistance in bacteria. This thesis addresses the problems of antibiotic resistance from a ”One Health” perspective. LÄS MER

  5. 25. Gene expression and antibiotic resistance in Escherichia coli from Swedish inland waters

    Författare :Sirirat Poonlapthawee; Jana Jass; Per-Erik Olsson; Allan Sirsjö; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi;

    Sammanfattning : Extensive use of antibiotics both from human-medicine and veterinary sources are believed to provide selective pressure on bacteria that leads to an increase in antibiotic resistance in environmental waters. Contamination of antibiotic resistant microbes will raise human health risks. LÄS MER