Sökning: "sub-MIC"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet sub-MIC.

  1. 1. Antibiotic resistance gone wild : A One Health perspective on carriage, selection and transmission of Extended-Spectrum Cephalosporinase- and Carbapenemase-producing Enterobacteriaceae

    Författare :Clara Atterby; Josef D. Järhult; Nicola Williams; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; E. coli; K. pneumoniae; ESBL; AmpC; Carbapenemase; ciprofloxacin resistance; colistin resistance; rural; wildlife; birds; sub-MIC; MSC; Cambodia; environment; epidemiology; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Antibiotics have saved millions of lives since they came into clinical use during the Second World War in the 1940s. Today, our effective use of antibiotics is under great threat due to emerging antibiotic resistance in bacteria. This thesis addresses the problems of antibiotic resistance from a ”One Health” perspective. LÄS MER

  3. 2. Mechanisms of Antibiotic Resistance Evolution

    Författare :Michael Knopp; Dan Andersson; Anca Segall; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance evolution; Escherichia coli; Salmonella; porins; fitness; epistasis; strain-specificity; sub-MIC; de novo gene evolution;

    Sammanfattning : The continuing emergence and spread of antibiotic resistant bacteria are a threat to various applications in modern medicine and impose a strong economic burden on health systems. The development of new antibiotics is slow and cannot counterbalance the dissemination of resistant bacteria. LÄS MER

  4. 3. Antibiotic interactions and selection for resistance in biofilms

    Författare :Po-Cheng Tang; Dan I. Andersson; Karin Hjort; Mark Webber; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotics; Mikrobiologi; Microbiology;

    Sammanfattning : The challenges posed by antibiotic-resistant bacteria in treating infections, particularly those associated with biofilms, require a deeper understanding of this lifestyle and its connection to resistance selection. Additionally, gaining insights into drug interactions is crucial for enhancing combination treatment efficacy and mitigating resistance development. LÄS MER

  5. 4. Plantaricins as a novel group of antibacterial compounds and enhancers of antibiotics

    Författare :Amani Musa; Hazem Khalaf; Torbjörn Bengtsson; Elena Vikström; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacteriocin; antimicrobial peptide; plantaricin; antibiotic resistance; PLNC8 αβ; ESKAPE pathogens;

    Sammanfattning : Antibiotics have revolutionized medicine, however, the rapid development of an-tibiotic resistance among bacteria is diminishing their efficacy. Antimicrobial pep-tides produced by Lactobacillus plantarum, i.e., plantaricins, are considered prom-ising alternatives to antibiotics against infections. LÄS MER

  7. 5. Gene expression and antibiotic resistance in Escherichia coli from Swedish inland waters

    Författare :Sirirat Poonlapthawee; Jana Jass; Per-Erik Olsson; Allan Sirsjö; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi;

    Sammanfattning : Extensive use of antibiotics both from human-medicine and veterinary sources are believed to provide selective pressure on bacteria that leads to an increase in antibiotic resistance in environmental waters. Contamination of antibiotic resistant microbes will raise human health risks. LÄS MER