Sökning: "Carbapenemase"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet Carbapenemase.

  1. 1. Antibiotic resistance gone wild : A One Health perspective on carriage, selection and transmission of Extended-Spectrum Cephalosporinase- and Carbapenemase-producing Enterobacteriaceae

    Författare :Clara Atterby; Josef D. Järhult; Nicola Williams; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; E. coli; K. pneumoniae; ESBL; AmpC; Carbapenemase; ciprofloxacin resistance; colistin resistance; rural; wildlife; birds; sub-MIC; MSC; Cambodia; environment; epidemiology; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Antibiotics have saved millions of lives since they came into clinical use during the Second World War in the 1940s. Today, our effective use of antibiotics is under great threat due to emerging antibiotic resistance in bacteria. This thesis addresses the problems of antibiotic resistance from a ”One Health” perspective. LÄS MER

  3. 2. Carbapenemase-Producing Enterobacteriaceae in Wastewater-Associated Aquatic Environments

    Författare :Faisal Ahmad Khan; Jana Jass; Bo Söderquist; Ann-Sofie Rehnstam-Holm; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance evolution; ESBL; Klebsiella; Multidrug; VIM;

    Sammanfattning : The emergence of carbapenem resistance due to the carbapenem-hydrolyzing enzymes (carbapenemases) in Enterobacteriaceae has led to limited therapeutic options. The increased resistance to these “last-resort” antibiotics is fueled by overuse and misuse of antibiotics in human medicine and agriculture. LÄS MER

  4. 3. Novel diagnostic methods for rapid characterization of extended-spectrum beta-lactamase- and carbapenemase-producing Enterobacteriaceae

    Författare :Muhammad Humaun Kabir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Klebsiella pneumoniae and Escherichia coli are two of the most clinically important pathogens of the family Enterobacteriaceae. Both can cause severe infections includ-ing urinary tract infections (UTI), bloodstream infections (BSI) and pneumonia. Both are also involved in dissemination of antibiotic resistance. LÄS MER

  5. 4. Dissemination of Multiresistant Bacteria : Their Selection, Transmission, Virulence and Resistance

    Författare :Gustaf Starlander; Åsa Melhus; Jørgen Vildershøj Bjørnholt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk bakteriologi; Clinical Bacteriology;

    Sammanfattning : Multiresistant bacteria are an emerging threat in modern medicine. Consumption of antimicrobial agents among humans, animals and in agriculture causes a selection of resistance genes. LÄS MER

  7. 5. The role of wastewater in surveillance and emergence of antibiotic resistant bacteria

    Författare :Marion Hutinel; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Bacteriology; Antibiotic resistance; Surveillance; Horizontal gene transfer; HGT; Conjugation; Plasmids; Epidemiology; CPE; E. coli; Carbapenamase; Linezolid; Colistin; Selection; sul4; OXA-48; gar; NDM; mcr; wastewater; sewage; sewer;

    Sammanfattning : As antibiotic resistance spreads among bacterial pathogens, it reduces treatment options and increases treatment failures of infectious diseases. Strategies employed to reduce this spread or adapt to its consequences need to be based on reliable surveillance data which is lacking in many countries, often due to limited resources. LÄS MER