Sökning: "alzheimer’s sciences"

Visar resultat 16 - 20 av 352 avhandlingar innehållade orden alzheimer’s sciences.

  1. 16. Characterization of Diagnostic Tools and Potential Treatments for Alzheimer’s Disease : PET ligands and BACE1 inhibitors

    Författare :Fredrik Jeppsson; Anna-Lena Ström; Kerstin Iverfeldt; Samuel Svensson; Martin Hallbeck; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer’s disease; Diagnostics; Treatment; PET ligand; BACE1; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Alzheimer’s disease (AD) is a very complex disorder and the most common form of dementia. The two pathological hallmarks of AD are extracellular amyloid-β (Aβ) plaques in cerebral cortex, and intraneuronal neurofibrillary tangles. LÄS MER

  3. 17. Amyloid Fibril Formation - Dye Detection and Effects of Lipids

    Författare :David Lindberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atomic force microscopy; fluorescence; Alzheimer’s disease; YOYO-1; amyloid fibrils; lipids; linear dichroism; FRET; circular dichroism; kinetics; Protein aggregation; insulin; thioflavin-T;

    Sammanfattning : Amyloid fibrils are long fibrillar homopolymers of self-assembled proteins. They can be formed by essentially any polypeptide, but are of particular interest because of their occurrence in several incurable and debilitating human diseases, e.g. Alzheimer’s disease (AD). LÄS MER

  4. 18. Structure and dynamics of amyloid-beta oligomers

    Författare :Faraz Vosough; Andreas Barth; Henrietta Nielsen; Oxana Klementieva; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; amyloid-beta peptide; Aβ oligomer; infrared spectroscopy; FTIR; protein aggregation; β-sheet; interaction; lithium; nickel; biokemi; Biochemistry;

    Sammanfattning : Alzheimer's disease (AD) is the most common cause of dementia, affects tens of millions of people all over the world and inflicts huge socioeconomic costs on the societies. AD is a neurodegenerative disease; it progresses over time and is highly debilitating at the advanced stages. LÄS MER

  5. 19. Characterization of muscarinic and nicotinic receptors in neural and non-neural tissue : changes in Alzheimer's disease

    Författare :Abdu Adem; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  7. 20. The influence of lysozyme and oligothiophenes on amyloid-β toxicity in models of Alzheimer’s disease

    Författare :Linnea Sandin; Katarina Kågedal; Ann-Christin Brorsson; Camilla Janefjord Warnqvist; Hanna Appelqvist; Susanne Frykman; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Alzheimer’s disease (AD) is a neurodegenerative disease and the most common cause of dementia worldwide. Apart from dominantly inherited mutations, age is the major risk factor and as life expectancy increases the prevalence for AD escalates dramatically. LÄS MER