Sökning: "Giant cell"
Visar resultat 1 - 5 av 39 avhandlingar innehållade orden Giant cell.
1. Giant cell arteritis. Epidemiological, morphological and molecular genetic studies
Sammanfattning : Giant cell arteritis (GCA) is a chronic inflammatory disorder of unknown etiology, affecting large and medium-sized arteries, predominantly in postmenopausal women. Its pathogenesis is probably multifactorial. Several studies suggest that GCA is an antigen-driven disease. LÄS MER
2. Medin Amyloid in Human Arteries and its Association with Arterial Diseases
Sammanfattning : Amyloid is a form of abnormal protein aggregation within the living body. Massive deposits can lead to organ failure. There is also increasing evidence that smaller pre-amyloid aggregates exert direct toxic effects to cells. LÄS MER
3. Giant Cell Arteritis - Pathogenetic and Epidemiological Aspects
Sammanfattning : Giant cell arteritis (GCA) is a chronic inflammatory disorder of medium-size and large arteries which affects people aged 50 years or older with a female preponderance. The two different expressions of GCA are temporal arteritis (TA) and polymyalgia rheumatica (PMR). LÄS MER
4. Predictors and early biomarkers in Giant Cell Arteritis
Sammanfattning : AbstractGiant Cell Arteritis (GCA) is the most common vasculitis in adults among people in the western world. The pathogenesis and etiology are not fully understood.In Study I, we investigated potential predictors for developing GCA, i.e. LÄS MER
5. Clinical and Epidemiological Studies on Giant Cell Arteritis
Sammanfattning : Objectives: The aim of the research summarized in this thesis was to present a comprehensive view of the epidemiology of biopsy-confirmed GCA, investigate infection as a possible risk factor of GCA, and to assess the association of GCA with cancer and myocardial infarction.Methods: To establish incidence and prevalence, patients diagnosed with biopsy-confirmed GCA in Skåne, Sweden 1997–2019 were identified through the database of the pathology department of Region Skåne which serves the entire region. LÄS MER