Sökning: "allelic association"

Visar resultat 16 - 20 av 53 avhandlingar innehållade orden allelic association.

  1. 16. Chronic Rhinosinusitis with Nasal Polyps - Symptoms, Heredity and Genetics

    Författare :Anton Bohman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nasal Polyps; Genetics; Signs and Symptoms; Genome-Wide Association Study; Gene Expression;

    Sammanfattning : ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by long-term inflammation of the paranasal sinuses combined with bilateral glassy protuberances from the middle meatus of the nasal cavity. This disease has an unknown cause, affects roughly 3% of the population and causes symptoms from the upper airways. LÄS MER

  3. 17. Suicide attempt and genes : psychiatric and genetic characteristics of suicide attempters

    Författare :Maj-Liz Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Suicide; Attempted; Mental disorders; Association; Genetic markers; Serotonin; Norepinephrine; Dopamine;

    Sammanfattning : Suicide affects an appreciable number of people in all societies. Finding genes that predispose to suicidal behavior may help to identify individuals at risk and an appropriate counseling and support can be extended to them. The studies of the present thesis focus on suicide attempt. LÄS MER

  4. 18. Molecular Genetic Studies of Sporadic and MEN1-Associated Endocrine Pancreatic Tumors

    Författare :Daniel Lindberg; Gunnar Westin; Göran Åkerström; Bo Wängberg; Uppsala universitet; []
    Nyckelord :Surgery; pancreatic endocrine tumor; MEN1; LOH; WNT7A; HDAC11; CDK4; CDKN2B p15; CDKN1B p27; CDKN2C p18; c-Myc; Smad4; pyrosequencing; epigenetic; methylation; tumor suppressor; Kirurgi;

    Sammanfattning : Pancreatic endocrine tumors (PETs) may cause typical syndromes of hormone excess, or appear clinically non-functioning without hormonal symptoms. PETs occur sporadically, in association with the multiple endocrine neoplasia type 1 (MEN1) syndrome, or rarely the von Hippel-Lindau syndrome. LÄS MER

  5. 19. Sequence evolution in a chromosomal region of Arabidopsis thaliana

    Författare :Jenny Hagenblad; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Växtgenetik; Plant genetics; flowering time; mapping; polymorphism; Linkage disequilibrium; Arabidopsis thaliana;

    Sammanfattning : Recently there has been a lot of interest in the use of liknage disequilibrium (LD) in genome wide scans for new genes, so called association mapping. Of crucial importance to a genome wide scan for associations between genetic markers and the trait of interest is the extent of LD, as it determines both how closely a trait can be mapped and also how many markers is needed to map it. LÄS MER

  7. 20. Genetic susceptibility to psoriasis in Sweden

    Författare :Fredrik Enlund; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD80; CD86; joint complaints; linkage analysis; NPL; psoriasis; TDT; chromosome region 3q21;

    Sammanfattning : A common skin disease affecting about 2-3% of the population, psoriasis has an inheritance pattern that is unclear, but most probably many genes are involved in its pathogenesis. Other studies have suggested many susceptibility regions in the genome, but as yet independent studies have replicated only some of these regions located on chromosome 1q, 6p and 17q. LÄS MER