Sökning: "VCAM-1"

Visar resultat 16 - 20 av 38 avhandlingar innehållade ordet VCAM-1.

  1. 16. Leukocyte-endothelial interactions in arteries in vivo : a new concept in the study of physiology and disease in large blood vessels

    Författare :Einar Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; leukocyte; cell adhesion molecule; chemokine; shear rate; capture; rolling; adhesion; subendothelial; cytokine; artery; intravital; in vivo;

    Sammanfattning : Pathophysiological events in large blood vessels contribute to immense morbidity and mortality in our society. A major clinical problem is a disease known as atherosclerosis. It involves a slow inflammatory deposition of lipid within the walls of large arteries that with time will weaken the arterial wall. LÄS MER

  3. 17. Mast Cell Progenitor Trafficking in Allergic Airway Inflammation

    Författare :Joakim Dahlin; Jenny Hallgren; Hans-Reimer Rodewald; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; mast cell progenitors; allergy; asthma; allergic airway inflammation; IgE; lung; CD11c;

    Sammanfattning : Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. LÄS MER

  4. 18. Autoimmune Regulator Deficient Mice, an Animal Model of Autoimmune Polyendocrine Syndrome Type I

    Författare :Signe Hässler; Ola Winqvist; Olle Kämpe; Bertrand Huard; Uppsala universitet; []
    Nyckelord :Molecular medicine; autoimmune regulator; autoimmune polyendocrine syndrome type I; peripheral tolerance; antigen presenting cells; autoimmunity; danger signal; knockout mice; Molekylärmedicin;

    Sammanfattning : Autoimmune diseases develop when the immune system fails to distinguish self from non-self or when the immune system is hypersensitive to endogenous or exogenous danger signals, or when a tissue erroneously sends a danger signal to the immune system. The education of the immune system to distinguish self from non-self is mainly carried out in the thymus and gives rise to central tolerance, whereas the ability to sense a danger or a healthy tissue constitutes peripheral tolerance. LÄS MER

  5. 19. The GH-IGF-1 Axis in Postmenopausal Women with Abdominal Obesity

    Författare :Celina Franco Ramos; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : Abdominal obesity is associated with blunted growth hormone (GH) secretion. GH treatment in abdominally obese men reduces visceral adipose tissue (VAT) and improves the metabolic profile. LÄS MER

  7. 20. Cardiac cell identification and isolation

    Författare :Laura Tarnawski; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Identification and isolation of cardiomyocytes from the heart, embryonic stem cells, or induced pluripotent stem cells is a challenging task and will require specific isolation techniques. Less than 30% of the cells within the murine heart are cardiomyocytes and, what is more, there are multiple sub-populations of cardiomyocytes like atrial, ventricular and conduction system cardiomyocytes. LÄS MER