Sökning: "T-cells"

Visar resultat 41 - 45 av 1144 avhandlingar innehållade ordet T-cells.

  1. 41. Regulation of immunity in Multiple Sclerosis : CD4+ T cells and the influence of natalizumab

    Författare :Måns Edström; Jan Ernerudh; Maria Jenmalm; Charlotte Dahle; Finn Sellebjerg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Multiple sclerosis (MS) is an autoimmune disease targeting the central nervous system (CNS) and the most common neurological cause of disability in young adults. In most cases, the disease course is characterised by the cycling of relapses and remissions, so called relapsing-remitting MS (RR-MS). LÄS MER

  3. 42. Diversity of CD1d-restricted natural killer T cells

    Författare :Markus Sköld; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; autoreactive; Ly49 receptor; CD1d; NKT cell; transplantation; Immunologi; serologi;

    Sammanfattning : The present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. LÄS MER

  4. 43. Acquisition and function of NK cell-associated molecules on T cells

    Författare :Erika Assarsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Natural killer cells; Natural Killer T cells; T cells; Receptors; Cytokines; Influenza A virus; Activation; Proliferation; Interactions;

    Sammanfattning : One challenge for multicellular organisms, including humans, is to cope with a broad variety of microorganisms and their rapid replication and alterations. To do this, both fast and specific defense mechanisms are needed that can control threatening infections. LÄS MER

  5. 44. Phenotype and function of CD25+ regulatory T cells in infants and adults

    Författare :Hanna Grindebacke; Göteborgs universitet; []
    Nyckelord :Immunology; CD4 CD25 FOXP3 regulatory T cells; human; allergy; IL-10; Systemic immunotherapy; migration; homing receptors; maturation;

    Sammanfattning : Active suppression by CD4+CD25+FOXP3+ regulatory T cells (Treg) is essential for the maintenance of peripheral tolerance to both self antigens and environmental antigens. Absence of these cells in human newborns leads to autoimmune and inflammatory disorders as well as allergic disease. LÄS MER

  7. 45. Immunoregulation in an experimental model of allergic asthma

    Författare :Magnus Korsgren; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; macrophage migration inhibitory factor; eosinophils; gd T cells; NK1.1 T cells; natural killer cells; immunoglobulins; B cells; innate immunity; allergic airway inflammation; immediate hypersensitivity; Physiology; Fysiologi; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. LÄS MER