Sökning: "Ly49 receptor"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Ly49 receptor.

  1. 1. Diversity of CD1d-restricted natural killer T cells

    Författare :Markus Sköld; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; autoreactive; Ly49 receptor; CD1d; NKT cell; transplantation; Immunologi; serologi;

    Sammanfattning : The present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. LÄS MER

  3. 2. NK cell inhibitory receptor interactions with MHC class I molecules

    Författare :Jonas Sundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; MHC class I molecules; inhibitory receptors;

    Sammanfattning : Natural killer (NK) cells represent the third population of lymphocytes in size after B- and T-cells. NK mediated killing of target cells is strongly influenced by MHC class I molecules expressed on target cells. In contrast to T-cells, NK cells can be inhibited by MHC class I molecules through the action of specific inhibitory NK cell receptors. LÄS MER

  4. 3. Intercellular protein transfer and regulation of inhibitory NK receptor accessibility

    Författare :Katja Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : NK cells are important players of innate immunity and capable of promoting specific responses of the adaptive immune system. NK cells possess the ability to recognise and eliminate virus-infected cells, tumour cells and allogeneic bone marrow grafts. LÄS MER

  5. 4. Decoding NK cell receptor specificity : functional and structural studies of MHC class 1 subcomponents

    Författare :Jakob Michaëlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; MHC class 1; inhibitory receptors;

    Sammanfattning : Natural Killer (NK) cells are an important part of the innate immune system. They can lyse target cells and secrete immunoregulatory cytokines early during immune responses. They mediate protection against viruses and tumours, and can reject MHC class I mismatched bone marrow grafts. LÄS MER

  7. 5. Dynamics of MHC class 1 recognition by natural killer cells : from receptor modulation to ligand acquisition

    Författare :Anna Sjöström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Natural killer (NK) cells are part of the innate immune system and can kill tumor cells and virus-infected cells without prior sensitization or clonal expansion. NK cells do not, in contrast to T and B cells, express any rearranged antigen-specific receptors. LÄS MER