Sökning: "Radionuclide imaging"

Visar resultat 21 - 25 av 88 avhandlingar innehållade orden Radionuclide imaging.

  1. 21. Realistic tissue dosimetry models using Monte Carlo simulations. Applications for radionuclide therapies

    Författare :Erik Larsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; internal dosimetry; radionuclide therapy; Monte Carlo; small scale dosimetry;

    Sammanfattning : Radionuclide therapy (RNT) is a generic term for treatment modalities that use a radionuclide labeled to a target-specific molecule. This so-called radiopharmaceutical accumulates in the target, where the ionizing radiation damages the cells. At sufficient levels of radiation, the cells cannot repair themselves. LÄS MER

  3. 22. Image Processing for Quantitative Scintillation-Camera Imaging. Application to Radionuclide Therapy

    Författare :Katarina Sjögreen Gleisner; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; 131-I; Clinical physics; SPECT; conjugate-view; volume quantification; activity quantification; image registration; image segmentation; medicinsk instrumentering; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; Radiopharmaceutical technology; Radiofarmaceutisk teknik;

    Sammanfattning : Individual-based determinations of the absorbed dose in radionuclide therapy largely rely on absolute measurement of the activity distribution and its redistribution over time. Scintillation-camera imaging is the most commonly employed measuring technique, applied in planar or SPECT mode, sometimes in combination with structural images from CT. LÄS MER

  4. 23. Computational and experimental methods for imaging and dosimetry in 177Lu radionuclide therapy : Classical and novel gamma cameras

    Författare :Daniel Roth; Lund Medicinsk strålningsfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radionuklidterapi; [177Lu]Lu-DOTA-TATE; Gammakamera; Aktivitetskvantifiering; Dosimetri; CdZnTe; Monte Carlo; Radionuclide therapy; [177Lu]Lu-DOTA-TATE; Gamma camera imaging; Activity quantification; Dosimetry; CdZnTe; Monte Carlo;

    Sammanfattning : Radionuclide therapy (RNT) is a form of radiotherapy that uses unsealed radioactive sources for the delivery of ionising radiation within a patient's body.Radiation dosimetry is not used routinely in all centres, and the RNT field can benefit from more data on pharmacokinetics and absorbed doses (ADs). LÄS MER

  5. 24. Affibody-mediated targeting of HER-family receptors for cancer imaging and therapy

    Författare :Charles Dahlsson Leitao; Stefan Ståhl; John Löfblom; Christoph Rader; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer therapy; radionuclide imaging; affibody molecules; HER-receptors; prodrug; protein design; Cancerterapi; radionuklidavbildning; affibody molekyler; HER-receptorer; prodrog; proteindesign; Bioteknologi; Biotechnology;

    Sammanfattning : Proteins are remarkable molecules with diverse and specialized functions playing essential roles in most biological processes. One such function is protecting us from diseases by the action of antibodies in our immune system that can recognize and mediate the destruction of invading pathogens by binding to foreign epitopes found on non-self proteins. LÄS MER

  7. 25. The ADAPT scaffold as a tool for diagnostic imaging and targeted therapy

    Författare :Emma von Witting; Sophia Hober; Inger Sandlie; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein G; ABD; ADAPT; affinity proteins; antibody; protein engineering; targeted therapy; nuclear medicine; molecular imaging; HER2; radionuclide therapy; Bioteknologi; Biotechnology;

    Sammanfattning : Molecular recognition, or the specific interactions between a protein and its ligand, is central to biology and a key factor for many different clinical and technical applications. Despite antibodies being only one of many different affinity proteins, it has by far been the most successful. LÄS MER