Sökning: "Radionuklidterapi"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Radionuklidterapi.

  1. 1. Computational and experimental methods for imaging and dosimetry in 177Lu radionuclide therapy : Classical and novel gamma cameras

    Författare :Daniel Roth; Lund Medicinsk strålningsfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Radionuklidterapi; [177Lu]Lu-DOTA-TATE; Gammakamera; Aktivitetskvantifiering; Dosimetri; CdZnTe; Monte Carlo; Radionuclide therapy; [177Lu]Lu-DOTA-TATE; Gamma camera imaging; Activity quantification; Dosimetry; CdZnTe; Monte Carlo;

    Sammanfattning : Radionuclide therapy (RNT) is a form of radiotherapy that uses unsealed radioactive sources for the delivery of ionising radiation within a patient's body.Radiation dosimetry is not used routinely in all centres, and the RNT field can benefit from more data on pharmacokinetics and absorbed doses (ADs). LÄS MER

  2. 2. Computational patient models for simulation of dynamic gamma-camera imaging : Application to renography and peptide receptor radionuclide therapy

    Författare :Gustav Brolin; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear medicine; Gamma camera; Renography; Radionuclide therapy; Internal dosimetry; Pharmacokinetics;

    Sammanfattning : Many nuclear medicine investigations rely on gamma-camera imaging to study and quantify the distribution of radiopharmaceuticals or radionuclides in the patient as a function of time. This is typically used for diagnostic studies of physiological functions or for calculation of absorbed doses following radionuclide therapy. LÄS MER

  3. 3. Image Processing for Quantitative Scintillation-Camera Imaging. Application to Radionuclide Therapy

    Författare :Katarina Sjögreen Gleisner; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; 131-I; Clinical physics; SPECT; conjugate-view; volume quantification; activity quantification; image registration; image segmentation; medicinsk instrumentering; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; Radiopharmaceutical technology; Radiofarmaceutisk teknik;

    Sammanfattning : Individual-based determinations of the absorbed dose in radionuclide therapy largely rely on absolute measurement of the activity distribution and its redistribution over time. Scintillation-camera imaging is the most commonly employed measuring technique, applied in planar or SPECT mode, sometimes in combination with structural images from CT. LÄS MER

  4. 4. Internal dosimetry. Macroscopic, small-scale and microscopic perspectives

    Författare :Cecilia Hindorf; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Nukleärmedicin; radiobiology; Nuclear medicine; B-cell lymphoma; Radioimmunotherapy; Radionuclide therapy; Internal dosimetry; Radiopharmaceutical technology; Radiofarmaceutisk teknik;

    Sammanfattning : Internal dosimetry deals with the assessment of absorbed dose for radionuclides distributed inside the body. The absorbed dose is in its turn used for correlation with the biological effect caused by the irradiation. LÄS MER

  5. 5. Realistic tissue dosimetry models using Monte Carlo simulations. Applications for radionuclide therapies

    Författare :Erik Larsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; internal dosimetry; radionuclide therapy; Monte Carlo; small scale dosimetry;

    Sammanfattning : Radionuclide therapy (RNT) is a generic term for treatment modalities that use a radionuclide labeled to a target-specific molecule. This so-called radiopharmaceutical accumulates in the target, where the ionizing radiation damages the cells. At sufficient levels of radiation, the cells cannot repair themselves. LÄS MER