Sökning: "Protein folding"
Visar resultat 16 - 20 av 243 avhandlingar innehållade orden Protein folding.
16. Protein Folding Simulations in Kink Model
Sammanfattning : The structure of protein is essentially important for life activities. Proteins can perform their functions only by specific structures. In this thesis, the kink and multi-kink model for protein description are reviewed. LÄS MER
17. Protein Folding Studies on the Ribosomal Protein S6: the Role of Entropy in Nucleation
Sammanfattning : One of the most challenging tasks remaining in the field of biochemistry is the one of understanding how the information within the amino acid sequence of proteins translates into a unique structure. Solving this problem would lead to endless possibilities for application in the medical and biotechnology industry. LÄS MER
18. Protein complexes : assembly, structure and function
Sammanfattning : Most proteins must fold into their native conformations to fulfil their biological functions. Failure of proteins to fold leads to cell pathology and a broad range of human diseases referred to as protein misfolding disease, e.g., Alzheimer’s disease, Parkinson’s disease, and type II diabetes. LÄS MER
19. Angiopoietin-like protein 4 : an unfolding chaperone regulating lipoprotein lipase activity
Sammanfattning : Lipoprotein lipase (LPL) is the main enzyme hydrolyzing triglyceride-rich lipoproteins in plasma. Proteoglycan-bound LPL on the vascular endothelium represent the functional pool of active enzyme. LPL is regulated in a tissue specific manner according to metabolic demands. LÄS MER
20. Statistical Physics of Protein Folding and Aggregation
Sammanfattning : The mechanisms of protein folding and aggregation are investigated by computer simulations of all-atom and reduced models with sequence-based potentials. A quasi local Monte Carlo update is developed in order to efficiently sample proteins in the folded phase. LÄS MER
