Sökning: "Lena Kjellen"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Lena Kjellen.
1. Studies on rat liver heparan sulfate proteoglycans
Sammanfattning : .... LÄS MER
2. Directing Angiogenesis : Cellular Responses to Gradients in vitro
Sammanfattning : Blood vessels are essential for the delivery of nutrients and oxygen to tissues, as well as for the removal of waste products. Patients with tumors, wounds or diabetes all have active angiogenesis, formation and remodeling of blood vessels, a process that is initiated and manipulated by gradients of secreted signaling proteins. LÄS MER
3. Cellular design of heparan sulfate : The NDST enzymes and their regulation
Sammanfattning : Heparan sulfate proteoglycans are proteins with long, unbranched heparan sulfate (HS) polysaccharide chains attached to them. They are found on cell surfaces and in basement membranes where they exert their action by interacting with a wide range of enzymes and signaling molecules and are thereby involved in a range of various processes both during embryonic development and in adult physiology. LÄS MER
4. Role of Heparan Sulfate N-sulfation in Mouse Embryonic Development
Sammanfattning : Heparan sulfate (HS) is a sulfated glycosaminoglycan expressed by all cells in the body. It is found at the cell surface and in the extracellular matrix where it binds a large amount of various ligands including growth factors and morphogens. LÄS MER
5. Implications of Heparan Sulfate and Heparanase in Inflammatory Diseases
Sammanfattning : Heparan sulfate (HS), an unbranched sulfated carbohydrate chain, and the HS-degrading enzyme heparanase play important roles in physiological and pathological processes during all stages of life, from early embryogenesis to ageing. Accumulated information shows that HS and heparanase are involved in inflammatory processes and associated diseases, e. LÄS MER