Sökning: "Jane Clarke"

Hittade 2 avhandlingar innehållade orden Jane Clarke.

1. 1. Protein folding studies of human superoxide dismutase and ALS associated mutants

   Författare :Mikael Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; superoxide dismutase; ALS; protein folding; equilibrium titration; protein stability; apo protein; disulphide bridge; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

   Sammanfattning : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. LÄS MER

3. 2. Protein Folding Studies on the Ribosomal Protein S6: the Role of Entropy in Nucleation

   Författare :Magnus Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; protein folding; circular permutation; topology; connectivity; entropy; protein stability; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

   Sammanfattning : One of the most challenging tasks remaining in the field of biochemistry is the one of understanding how the information within the amino acid sequence of proteins translates into a unique structure. Solving this problem would lead to endless possibilities for application in the medical and biotechnology industry. LÄS MER