Sökning: "Progenitor cells"
Visar resultat 21 - 25 av 417 avhandlingar innehållade orden Progenitor cells.
21. Studies of Mesenchymal Progenitor Cells and Tumour Growth, Integrins and Matrix Metalloproteinases
Sammanfattning : In this thesis we characterize the effect of mesenchymal progenitor cells (MPCs) on tumour growth, and show that MPCs can have inhibitory effects on tumour development. We developed a method to subcutaneously transplant tumour cells, cultured in vitro in a pre-formed gelatin matrix, that made it possible to study the early phases of tumour development. LÄS MER
22. Intrinsic and extrinsic factors controlling the differentiation of human midbrain progenitor cells
Sammanfattning : Parkinson's disease (PD) is a common neurodegenerative disorder characterized by motor deficits. Levodopa treatment provides marked symptomatic relief. However, within 5-10 years after the start of Levodopa treatment, most PD patients display a gradual loss of drug efficacy. LÄS MER
23. Stem cell function and organ development : analysis of Lhx2 function in hematopoietic stem cells and eye development
Sammanfattning : When a multicellular organism suffers damages to tissues/organs it heals itself by either substituting the lost cellular matrix by scar formation or by regenerating the lost tissue. Regeneration likely occurs by a recapitulation of the developmental process that formed the organ. LÄS MER
24. Alveolar Progenitor Cells in Lung Damage and Regeneration in Pulmonary Fibrosis
Sammanfattning : .... LÄS MER
25. Cellular pathways and molecular regulation of hematopoietic stem cells
Sammanfattning : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. LÄS MER