Sökning: "bleomycin model"

Hittade 3 avhandlingar innehållade orden bleomycin model.

1. 1. Alveolar Progenitor Cells in Lung Damage and Regeneration in Pulmonary Fibrosis

   Författare :Victoria Ptasinski; NanoLund: Centre for Nanoscience; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; idiopathic pulmonary fibrosis IPF ; alveolar epithelium; aberrant basaloid cells; bleomycin model; induced pluripotent stem cells;

   Sammanfattning : .... LÄS MER

3. 2. Galectin Inhibitors – Molecular Tools in Biomedical Research and Clinical Implications

   Författare :John Stegmayr; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectins; inhibitors; evaluation assays; cell culture; idiopathic pulmonary fibrosis; synthetic small-molecule galectin inhibitors; plant-derived polysaccharides;

   Sammanfattning : Galectins are β-galactoside-binding lectins, which are present in both the intracellular and extracellular environments of cells. During the last two decades, galectins have gained increasing interest as drug targets in various diseases, such as chronic inflammation (fibrosis) and cancer, in which galectins have been shown to play important, and sometimes rate-limiting, roles. LÄS MER

4. 3. The role of chromatin in the induction and repair of DNA damage

   Författare :Mats Ljungman; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA damage; Chromatin; Kromatin; DNA;

   Sammanfattning : The role of chromatin in the induction and repair of DNA damage has a dual nature.The constituent proteins of chromatin protect the DNA against the induction of DNAdamage, while at the same time they reduce the accessibility of DNA to repair enzymes. LÄS MER