Sökning: "NPY"

Visar resultat 31 - 35 av 125 avhandlingar innehållade ordet NPY.

  1. 31. Biochemical characterisation and clinical correlation of neuropeptides in neuroblastoma with emphasis on neuropeptide Y

    Författare :Per Bjellerup; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :chromatography; CPON; ganglioneuroma; mass spectrometry; neuroblastoma; neuropeptide Y; pancreastatin; phaeochromocytoma; primary structure; radioimmunoassay; somatostatin; vasoactive intestinal peptide;

    Sammanfattning : Neuropeptides influence cellular events involved in tumour growth and differentiation. Neuroblastoma, a malignant childhood tumour of neural crest origin, synthesises and releases monoamines and neuropeptides. The concentrations of some of these neuropeptides in plasma are correlated to clinical stage and outcome. LÄS MER

  3. 32. Novel mechanism of action of antipsychotic drugs : effects on neuropeptides in rat brain

    Författare :Susanne H M Gruber; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Schizophrenia; D-amphetamine; Antipsychotic drugs; Neurotensin; Neuropeptide Y; Rat brain; Microdialysis;

    Sammanfattning : Schizophrenic patients have been reported to have lower concentrations of neurotensin (NT)-like immunoreactivity (-LI) in their cerebrospinal fluid (CSF) that normalize after treatment with antipsychotic drugs. Schizophrenic patients also had higher CSF concentrations of neuropeptide Y (NPY)-LI compared to controls, thus involvement of NPY in the disease has also been suggested. LÄS MER

  4. 33. Distribution and regulation of neuropeptide Y and its receptors in the human and rat brain : role in affective disorders

    Författare :Laura Caberlotto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :neuropeptide Y; neuropeptide Y receptors; human; depression; Flinder Sensitive Line rats; in situ hybridization; receptor autoradiography; immunohistochemistry;

    Sammanfattning : Neuropeptide Y (NPY) is one of the most abundant peptides found within the mammalian brain. Many studies have documented that this 36-amino acid peptide exerts a wide range of central effects. LÄS MER

  5. 34. Stress-related peptides in suicide attempters

    Författare :Åsa Westrin; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; temperament; cortisol; neuropeptide Y; delta sleep-inducing peptide; somatostatin; beta-endorphin; corticotropin-releasing hormone; hypothalamic pituitary adrenal axis; attempted suicide; affective disorders; Psychiatry; clinical psychology; psychosomatics; Psykiatri; klinisk psykologi; psykosomatik;

    Sammanfattning : A suicide attempt is the best known predictor of completed suicide. It has long been assumed that most suicide attempts are the results of stress. LÄS MER

  7. 35. Central neuropeptide Y (NPH) expression and function : role in stress, experimental anxiety, and cognition

    Författare :Annika Thorsell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :neuropeptide Y; stress; experimental anxiety; cognition; lipid-mediated gene transfer; transgenic animals; rat;

    Sammanfattning : Neuropeptide Y (NPY), a 36 amino acid peptide abundantly expressed throughout the mammalian nervous system, has been implicated in experimental anxiety and stress related responses, feeding, and learning and memory. These functions are mediated via different receptor subtype populations (Y1-Y6), all belonging to the G-protein coupled receptor superfamily. LÄS MER