Sökning: "NADPH"

Visar resultat 1 - 5 av 159 avhandlingar innehållade ordet NADPH.

  1. 1. Plant type II NAD(P)H dehydrogenases : Structure, regulation and evolution of NDB proteins

    Författare :Mengshu Hao; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis; Ca2 ; Electron transport; NDH-2; NDB; pH; NADH; NADPH; Plant mitochondria; Potato; Type II NAD P H dehydrogenase;

    Sammanfattning : In living organisms, respiration is a biological process degrading different carbon substrates, consuming O2, and releasing the carbon as CO2. Plants have several alternative enzymes that are involved in the respiratory processes, as compared to animals. LÄS MER

  2. 2. Transport and release of insulin granules during biphasic insulin secretion

    Författare :Rosita Ivarsson; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; granule transport; Myosin 5a; Cyclic AMP; NADPH; Motor protein; Insulin secretion; Cytoskeleton;

    Sammanfattning : Glucose-evoked insulin secretion exhibits two phases: The first phase represents exocytosis of insulin granules situated at the plasma membrane, whereas the second phase reflects insulin release from granules continuously recruited to the plasma membrane. This thesis investigates different aspects of phasic insulin secretion, with the specific aims to elucidate the possible contribution of insulin granule transport, as well as to study the influence of the nucleotides cAMP and NADPH to this process. LÄS MER

  3. 3. Metabolic engineering of Saccharomyces cerevisiae for polyhydroxybutyrate production

    Författare :Kanokarn Kocharin; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; S. cerevisiae; Acetyl-CoA; NADPH; Metabolic engineering; Polyhydroxybutyrate;

    Sammanfattning : Establishing industrial biotechnology for the production of chemical compounds from the biosynthetic pathway has received a significant boost with the implementation of metabolic engineering. At present, metabolic engineering in Saccharomyces cerevisiae gains significant advantages of integration of knowledge acquired through a long history of use and data acquisition from novel –omics technologies hence enabling the development of a tailor-made S. LÄS MER

  4. 4. The Role of Reactive Oxygen Species in Animal Models of Autoimmunity

    Författare :Malin Hultqvist; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mice; Phytol; ROS; NOX; NADPH; p47phox; Ncf1; EAE; inflammation; Arthritis; RA; MS; Rats; Autoimmunity;

    Sammanfattning : Reactive oxygen species (ROS) produced by the phagocyte NADPH oxidase complex are important in the killing of invading pathogens. Lately, a role of ROS has been suggested in regulation of the immune system. LÄS MER

  5. 5. Evaluation of precursor and cofactor engineering strategies influencing fatty acid metabolism in Saccharomyces cerevisiae

    Författare :Alexandra Linda Bergman; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Saccharomyces cerevisiae; metabolic engineering; fatty acids; oleochemicals; NADPH; Sustainability; phosphoketolase; acetyl-CoA; transcription factor;

    Sammanfattning : If humanity is to reduce the rate of climate change, it is essential that our societies switch to a more sustainable production of fuels and chemicals, which in turn depends on technological development. Oleochemical production via microbial catalysts – such as the yeast Saccharomyces cerevisiae – can use a considerably broader range of renewable substrates compared to the conventional production processes. LÄS MER