Sökning: "Motor protein"

Visar resultat 1 - 5 av 173 avhandlingar innehållade orden Motor protein.

  1. 1. Stochastic modeling of motor proteins

    Författare :Martin Lindén; Mats Wallin; Dean Astumian; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molecular motor; motor protein; Markov process; fluctuations; statistical mechanics; microscopic reversibility; Physics; Fysik;

    Sammanfattning : Motor proteins are microscopic biological machines that convert chemical energy into mechanical motion and work. They power a diverse range of biological processes, for example the swimming and crawling motion of bacteria, intracellular transport, and muscle contraction. LÄS MER

  3. 2. Myosin 1c taking adrenergic metabolism for a spin : More than a motor protein

    Författare :Alice Åslund; Tore Bengtsson; Michael Czech; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose uptake; Glucose transporter; Brown adipose tissue; White adipose tissue; Skeletal muscle; Myosin1c; Nuclear myosin I; Physiology; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Metabolic diseases like type II diabetes (T2D) and obesity largely stems from an unbalanced energy homeostasis with the fails of the insulin pathway to the point in which the glucose homeostasis is severely disturbed leading to hyperglycemia. We have investigated if the β-adrenergic signaling pathways, in both brown adipose tissue (BAT) and skeletal muscle, could be used as a strategy to alleviate metabolic disease. LÄS MER

  4. 3. Creation of a Nanometer-Scale Toolbox for Molecular Motor Transport-Circuits

    Författare :Richard Bunk; Fasta tillståndets fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Coating and surface treatment; materialteknik; Materiallära; Material technology; Produktionsteknik; Production technology; Semiconductory physics; Halvledarfysik; Proteins; enzymology; Proteiner; enzymologi; reumatologi; Physics; Fysik; muskelsystem; Skelett; rheumatology locomotion; muscle system; Skeleton; Biofysik; Biophysics; Biomedicinska vetenskaper; Biomedical sciences; fluorescence microscopy; EBL; T-profile channel; nano-imprinting; cargo; quantum dot; silane; myosin; actin; motor protein; factory-on-a-chip; toolbox; lab-on-a-chip; molecular motor; nanotechnology; Biokemisk teknik; Biotechnology; Bioteknik; Skikt och ytbehandling; Biochemical technology;

    Sammanfattning : This thesis presents studies of molecular motors in interaction with nm-scale structures, as well as the development of a set of tools that can be used for the construction of custom-designed nano-transportation systems. In our studies, we have used the latest nanoscale technology and combined this with advanced results from chemistry and biomedical sciences. LÄS MER

  5. 4. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics

    Författare :Joachim Piguet; Horst Vogel; Ruud Hovius; Jerker Widengren; Antoine Triller; Switzerland Ecole Polytechnique Fédérale de Lausanne (EPFL); []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence; microscopy; plasma membrane; membrane proteins; membrane proteins diffusion; single-molecule imaging; single-molecule tracking; pentameric ligand-gated ion channels; nicotinic acetylcholine receptor; serotonin receptor; synapse; neuromuscular junction; post-synaptic scaffold; rapsyn; myopathies; fluorescent proteins; Förster resonance energy transfer; FRET imaging; protein-protein interactions; protein trafficking; photo-activatable proteins; Biological Physics; Biologisk fysik;

    Sammanfattning : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. LÄS MER

  7. 5. Zinc in folding and misfolding of SOD1 : Implications for ALS

    Författare :Lina Leinartaité; Mikael Oliveberg; Bengt-Harald Jonsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein stability; protein misfolding; local unfolding; metal binding; energy landscape; protein disease; amyotrophic lateral sclerosis; Biochemistry; biokemi;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing degeneration of upper and lower motor neurons. Most ALS cases are sporadic; only 6% are associated with mutations in Cu, Zn superoxide dismutase (SOD1). LÄS MER