Sökning: "p47phox"

Hittade 2 avhandlingar innehållade ordet p47phox.

1. 1. The Role of Reactive Oxygen Species in Animal Models of Autoimmunity

   Författare :Malin Hultqvist; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mice; Phytol; ROS; NOX; NADPH; p47phox; Ncf1; EAE; inflammation; Arthritis; RA; MS; Rats; Autoimmunity;

   Sammanfattning : Reactive oxygen species (ROS) produced by the phagocyte NADPH oxidase complex are important in the killing of invading pathogens. Lately, a role of ROS has been suggested in regulation of the immune system. LÄS MER

3. 2. Reactive oxygen and nitrogen in host defence against Francisella tularensis

   Författare :Helena Lindgren; Anders Sjöstedt; Tommy Sundquist; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Francisella tularensis; inducible nitric oxide synthase; phagocyte oxidase; macrophages; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; klinisk bakteriologi; Clinical Bacteriology;

   Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Initially upon infection of the host, intramacrophage proliferation of F. tularensis occurs but after activation of the acquired host immunity, the phagocytes become activated to kill the bacterium. In my thesis, I focused on mechanisms utilized by F. LÄS MER