Sökning: "Ionizing Radiation"

Visar resultat 26 - 30 av 166 avhandlingar innehållade orden Ionizing Radiation.

  1. 26. Studies of DNA repair strategies in response to complex DNA damages

    Författare :Ainars Bajinskis; Mats Harms-Ringdahl; Bo Stenerlöw; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ionizing radiation; complex DNA damage; indirect effect of radiation; dimethyl sulfoxide; molekylärgenetik; Molecular Genetics;

    Sammanfattning : The main aim of this thesis was to study the role of the indirect actions of γ-rays and α-particles on the complexity of primary DNA damages and the repair fidelity of major DNA repair pathways: non-homologous end joining (NHEJ), homologous recombination repair (HRR) and base excision repair (BER). The complexity of radiation-induced damages increases and the proximity between damages decreases with increasing LET due to formation of ionization clusters along the particle track. LÄS MER

  3. 27. Single event upset : a consequence of ionizing radiation in electronic circuits

    Författare :Dezso Novák; KTH; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  4. 28. Characterizing and modulating the effects of ionizing radiation to the juvenile hippocampus

    Författare :Malin Blomstrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; low-dose radiation; CNS; hippocampus; apoptosis; cytokines; growth factors; microglia; medulloblastoma; hippocampal sparing; tumor bed boost; cognitive risk estimation;

    Sammanfattning : Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with late side effects e.g. LÄS MER

  5. 29. Neonatal Exposure to Low-Dose Ionizing Radiation in Mice : Developmental Neurotoxic Effects of Single and Fractionated Doses and Interaction with Nicotine

    Författare :Sonja Buratovic; Per Eriksson; Jack Valentin; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : This thesis aims to investigate the developmental neurotoxic effects of low-dose exposure to ionizing radiation, alone or together with nicotine, during a defined critical period of neonatal brain development in mice. Investigation of neurotoxic effects following fractionated or acute low-dose radiation, resembling the clinical situation during repeated CT scans or radiation delivered to non-target tissue during radiotherapy, and possible interaction effects with other agents, is of great importance for risk and safety evaluation. LÄS MER

  7. 30. New tools for probing biological extremes of ionizing radiation

    Författare :Charlotta Nilsson; Kärnfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fysicumarkivet A:000;

    Sammanfattning : Three different biological extremes of irradiation of living organisms, both human and animal, have been investigated and are presented in this thesis. Central to the thesis is the concept of bystander effects of ionizing radiation, i.e. LÄS MER