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Visar resultat 16 - 20 av 28 avhandlingar som matchar ovanstående sökkriterier.

  1. 16. Imaging of the brain opioid system in amphetamine dependence

    Författare :Joar Guterstam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Amphetamine dependence is a global health problem, often giving rise to severe medical and social complications in affected individuals. Unfortunately, there is still limited evidence for any specific treatment that would help amphetamine dependent patients to avoid relapse. LÄS MER

  3. 17. Clonidine in pediatric anesthesia : aspects on population pharmacokinetics, nasal administration and safety

    Författare :Peter Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Clonidine is widely use as premedication in pediatric patients and has many beneficial effects in the perioperative period. The introduction of population pharmacokinetics in the 1980s has proven useful when performing pharmacokinetic studies in children to circumvent previous limitations with traditional pharmacokinetics. LÄS MER

  4. 18. Pharmacokinetics - Effect Relations of Glibenclamide and its Metabolites in Humans

    Författare :Tony S Rydberg; Institutionen för hälsovetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal insufficiency.; insulin; glucose; non-insulin dependent; diabetes mellitus; pharmacodynamic modelling; pharmacodynamics; pharmaco-kinetics; HPLC method; Glibenclamide; sulphonylurea; metabolites; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Glibenclamide (Gb) is the most commonly employed sulphonylurea worldwide for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). There has been uncertainty concerning its pharmacokinetics (PK) and pharmacodynamics (PD). LÄS MER

  5. 19. Nursing and anaesthesia care of growing pigs

    Författare :Anneli Rydén; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : The overall aim of the present thesis was to improve the welfare of animals in research by refining the perioperative nursing and anaesthesia care of growing pigs in accordance with the 3Rs, replace, reduce and refine.Forty-six pigs were trained during a 14-day acclimatisation period to accept blood and urine sampling and ultrasound examination. LÄS MER

  7. 20. Molecular epidemiology of hepatitis A, B and C in Estonia

    Författare :Tatjana Tallo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HAV; HBV; HCV; strains; genotype; phylogenetic analysis;

    Sammanfattning : During the last decade changes have occurred in the epidemiology of hepatitis A, B and C in Estonia. A shift from high to intermediate endemicity for HAV has led to a shift in age of susceptible individuals from children to adolescents and adults. LÄS MER