Sökning: "Immunotherapy"

Visar resultat 36 - 40 av 288 avhandlingar innehållade ordet Immunotherapy.

  1. 36. On immunotherapy against prostate cancer

    Författare :Kajsa Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostate cancer (PC) is the most frequently diagnosed cancer in Swedish men, with an incidence of around 9000 cases per year, and the main cause of cancer related death. Standard treatment includes surgery, radiotherapy and hormonal therapy. LÄS MER

  3. 37. Experimental models of pediatric brain tumors. Establishment, immunophenotyping and clinical implications

    Författare :Emma Sandén; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric Brain Tumor; Experimental model; Immunotherapy; Immune monitoring; Medulloblastoma;

    Sammanfattning : Brain tumors are the most common solid tumors in children. Current treatment protocols fail in 25% of patients and are associated with significant long-term adverse effects in survivors. LÄS MER

  4. 38. Restoring antitumor immunity with dendritic cell reprogramming strategies. Reprogramming cancer cells to antigen-presenting cells

    Författare :Alexandra Gabriela Barros Ferreira; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell Reprogramming; Cancer cells; Tumor Antigen-presenting Cells; immunotherapy;

    Sammanfattning : For the past two decades, immunotherapy revolutionized cancer treatment. However, responses vary significantly among eligible patients and some cancer types are not yet open to immunotherapy. Several mechanisms contribute to immunotherapy resistance, including loss of antigen presentation machinery and immunosuppression. LÄS MER

  5. 39. Gene and Protein Expression in Human Gliomas

    Författare :Oscar Persson; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumour associated antigen; immunotherapy; glioma; targeted therapy; microarray; proteomics;

    Sammanfattning : The human gliomas are the most common primary brain tumours. They are highly aggressive with a rapid fatal progression for the patient. The invasive growth pattern and inherent resistance to radiation and chemotherapy account for a lack of efficient therapies. LÄS MER

  7. 40. Preclinical evaluation of immunostimulatory gene therapy for pancreatic cancer

    Författare :Emma Eriksson; Angelica Loskog; Tanja de Gruijl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; immunotherapy; oncolytic viruses; adenoviruses; CD40L; 4-1BBL; IL-6; tumor microenvironment; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Pancreatic cancer is characterized by its desmoplastic tumor microenvironment and the infiltration of immunosuppressive cells. It is a devastating disease where most patients are diagnosed at a late stage and the treatment options are few. The development of new treatments is surly needed. LÄS MER