Sökning: "Immune monitoring"

Visar resultat 1 - 5 av 99 avhandlingar innehållade orden Immune monitoring.

  1. 1. Cellular Immune Responses to Allografts and Cytomegalovirus

    Författare :Mats Engstrand; Olle Korsgren; Gunnar Tufveson; Nils Persson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Transplantation; Rejection; Monitoring; Flow Cytometry; MHC; Tetramer; CMV; infection; Immunologi; Immunology; Immunologi;

    Sammanfattning : Today the immunosuppressive treatment is kept to a level were the incidence of acute rejection is below 20% within the first year after transplantation. As a consequence, a group of transplanted patients is over-immunosuppressed and at risk for infections. LÄS MER

  3. 2. Interferon-alpha based treatment of metastatic malignant melanoma : Effect of immune parameters of importance for monitoring immunotherapy

    Författare :Annika Håkansson; Sten Nilsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cutaneous malignant melanoma is a rapidly increasing disease. Most patients are cured by surgical excision of their primary tumour, but for patients with metastatic disease the prognosis is still very poor despite various attempts with chemotherapeutic agents, and during the last decade with immunotherapy, using several different biological agents alone or in combination. LÄS MER

  4. 3. Experimental models of pediatric brain tumors. Establishment, immunophenotyping and clinical implications

    Författare :Emma Sandén; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatric Brain Tumor; Experimental model; Immunotherapy; Immune monitoring; Medulloblastoma;

    Sammanfattning : Brain tumors are the most common solid tumors in children. Current treatment protocols fail in 25% of patients and are associated with significant long-term adverse effects in survivors. LÄS MER

  5. 4. Maternal and neonatal metabolomes and their associations to immune maturation and allergy in early life

    Författare :Olle Hartvigsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Untargeted Metabolomics; allergy; QC; quality control; plasma; umbilical cord; placenta; LC-MS; immune system;

    Sammanfattning : Allergy, one of the most common chronic diseases worldwide, is caused by a dysregulated immune system reacting to normally harmless proteins. However, regulating mechanisms are not well understood. The aim of this thesis was to investigate if plasma and placenta metabolites associate prospectively to allergy development and immune maturation. LÄS MER

  7. 5. Immune monitoring in humans after manipulation by B cell depletion and immunization

    Författare :Therese Vallerskog; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The overall goal of this thesis was to study the influence of immunomodulatory drugs on the human immune system. The approach was bi-directional; ex vivo studies were performed after B cell depletion with rituximab treatment in patients with SLE and RA, and an in vivo assay was established to study effects of drugs on immune responsiveness. LÄS MER